Zinc in PDB 7r4f: Bovine Complex I in the Presence of IM1761092, Slack Class I (Composite Map)

All present enzymatic activity of Bovine Complex I in the Presence of IM1761092, Slack Class I (Composite Map):
1.6.5.3; 1.6.99.3; 7.1.1.2;

The structure of Bovine Complex I in the Presence of IM1761092, Slack Class I (Composite Map) also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Potassium	(K)	1 atom
Iodine	(I)	1 atom
Iron	(Fe)	28 atoms
Chlorine	(Cl)	1 atom

The binding sites of Zinc atom in the Bovine Complex I in the Presence of IM1761092, Slack Class I (Composite Map) (pdb code 7r4f). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Bovine Complex I in the Presence of IM1761092, Slack Class I (Composite Map), PDB code: 7r4f:

Zinc binding site 1 out of 1 in the Bovine Complex I in the Presence of IM1761092, Slack Class I (Composite Map)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Bovine Complex I in the Presence of IM1761092, Slack Class I (Composite Map) within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn201 b:55.3 occ:1.00 NE2 R:HIS68 2.0 31.5 1.0 SG R:CYS84 2.2 36.7 1.0 SG R:CYS87 2.3 35.2 1.0 SG R:CYS59 2.4 36.2 1.0 CE1 R:HIS68 2.9 31.5 1.0 CD2 R:HIS68 3.1 31.5 1.0 CB R:CYS84 3.2 36.7 1.0 CB R:CYS87 3.4 35.2 1.0 CB R:CYS59 3.5 36.2 1.0 N R:GLY61 3.6 35.2 1.0 N R:CYS87 3.8 35.2 1.0 CA R:GLY61 3.9 35.2 1.0 ND1 R:HIS68 4.0 31.5 1.0 CA R:CYS87 4.1 35.2 1.0 CG R:HIS68 4.2 31.5 1.0 C R:CYS59 4.4 36.2 1.0 CB R:TYR86 4.5 31.0 1.0 C R:ASP60 4.5 35.0 1.0 CA R:CYS59 4.6 36.2 1.0 O R:CYS59 4.6 36.2 1.0 N R:ASP60 4.6 35.0 1.0 CA R:CYS84 4.6 36.7 1.0 C R:TYR86 4.8 31.0 1.0 C R:CYS87 4.8 35.2 1.0 CA R:ASP60 4.9 35.0 1.0 N R:GLY88 4.9 36.9 1.0 N R:TYR86 5.0 31.0 1.0

H.R.Bridges, J.N.Blaza, Z.Yin, I.Chung, M.N.Pollak, J.Hirst. Structural Basis of Mammalian Respiratory Complex I Inhibition By Medicinal Biguanides. Science V. 379 351 2023.
ISSN: ESSN 1095-9203
PubMed: 36701435
DOI: 10.1126/SCIENCE.ADE3332