Zinc in PDB 7qqd: Nuclear Factor One X - Nfix in P21

The structure of Nuclear Factor One X - Nfix in P21, PDB code: 7qqd was solved by M.Lapi, A.Chaves-Sanjuan, L.J.Gourlay, M.Tiberi, M.Polentarutti, N.Demitri, G.Bais, M.Nardini, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.18 / 2.70
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	43.171, 98.358, 61.629, 90, 92.7, 90
R / Rfree (%)	19.5 / 24.3

The binding sites of Zinc atom in the Nuclear Factor One X - Nfix in P21 (pdb code 7qqd). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Nuclear Factor One X - Nfix in P21, PDB code: 7qqd:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Nuclear Factor One X - Nfix in P21


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Nuclear Factor One X - Nfix in P21 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:85.7 occ:1.00 SG A:CYS156 1.7 57.1 1.0 ND1 A:HIS167 2.0 71.2 1.0 SG A:CYS162 2.2 53.9 1.0 SG A:CYS103 2.4 70.5 1.0 CE1 A:HIS167 2.8 66.1 1.0 CB A:CYS162 3.0 52.3 1.0 CB A:CYS156 3.2 52.7 1.0 CG A:HIS167 3.2 68.5 1.0 CB A:CYS103 3.4 51.5 1.0 CA A:CYS103 3.5 66.1 1.0 CA A:CYS156 3.6 65.7 1.0 CB A:HIS167 3.7 62.9 1.0 NE2 A:HIS167 4.0 59.3 1.0 CD2 A:HIS167 4.2 52.7 1.0 N A:CYS103 4.3 67.0 1.0 N A:SER157 4.4 59.3 1.0 C A:CYS156 4.4 53.0 1.0 CA A:CYS162 4.5 68.3 1.0 CB A:GLN164 4.6 49.5 1.0 C A:CYS103 4.7 69.0 1.0 N A:VAL104 4.7 63.1 1.0 N A:ASN158 4.7 76.5 1.0 N A:CYS156 4.8 51.1 1.0 CE A:LYS152 4.8 61.5 1.0 O A:GLN155 5.0 77.0 1.0

Zinc binding site 2 out of 4 in the Nuclear Factor One X - Nfix in P21


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Nuclear Factor One X - Nfix in P21 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:86.6 occ:1.00 ND1 B:HIS166 2.1 53.2 1.0 ND1 A:HIS166 2.4 63.5 1.0 CE1 B:HIS166 2.7 60.4 1.0 CE1 A:HIS166 3.3 73.8 1.0 CG B:HIS166 3.3 42.6 1.0 CG A:HIS166 3.5 56.5 1.0 O A:HOH334 3.5 45.8 1.0 CB A:HIS166 3.8 54.6 1.0 CB B:HIS166 3.9 43.1 1.0 NE2 B:HIS166 4.0 44.3 1.0 CA A:HIS166 4.2 42.6 1.0 CD2 B:HIS166 4.3 52.8 1.0 CA B:HIS166 4.3 41.4 1.0 NE2 A:HIS166 4.4 65.1 1.0 O B:HOH325 4.5 45.0 1.0 CD2 A:HIS166 4.6 63.8 1.0 N A:HIS166 4.9 49.5 1.0 O B:HOH320 4.9 64.6 1.0

Zinc binding site 3 out of 4 in the Nuclear Factor One X - Nfix in P21


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Nuclear Factor One X - Nfix in P21 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:64.5 occ:1.00 ND1 B:HIS167 2.0 58.3 1.0 SG B:CYS156 2.1 59.8 1.0 SG B:CYS103 2.3 73.5 1.0 SG B:CYS162 2.4 50.1 1.0 CE1 B:HIS167 2.8 59.8 1.0 CB B:CYS156 2.9 52.2 1.0 CG B:HIS167 3.1 64.9 1.0 CB B:CYS162 3.1 57.7 1.0 CB B:CYS103 3.4 49.0 1.0 CA B:CYS156 3.4 72.2 1.0 CB B:HIS167 3.6 46.1 1.0 CA B:CYS103 3.8 58.9 1.0 NE2 B:HIS167 4.0 57.5 1.0 CD2 B:HIS167 4.2 60.1 1.0 C B:CYS156 4.4 74.5 1.0 N B:SER157 4.5 95.1 1.0 N B:CYS156 4.5 69.4 1.0 CB B:GLN164 4.6 44.1 1.0 CA B:CYS162 4.6 69.0 1.0 N B:CYS103 4.6 65.2 1.0 CD B:LYS152 4.8 51.1 1.0 N B:ASN158 4.9 70.7 1.0

Zinc binding site 4 out of 4 in the Nuclear Factor One X - Nfix in P21


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Nuclear Factor One X - Nfix in P21 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn202 b:83.4 occ:1.00 OD1 B:ASP90 2.0 85.3 1.0 OD2 B:ASP90 2.2 56.2 1.0 CG B:ASP90 2.4 70.0 1.0 SG B:CYS102 2.6 67.3 1.0 CB B:CYS102 3.4 77.2 1.0 CB B:ASP90 3.9 69.0 1.0 NZ B:LYS99 3.9 57.9 1.0 CE B:LYS99 4.2 61.7 1.0 O B:CYS103 4.6 65.0 1.0 CA B:CYS102 4.8 71.5 1.0 CA B:ASP90 4.8 61.6 1.0 CD B:LYS99 4.9 63.2 1.0 C B:CYS102 5.0 64.2 1.0

M.Lapi, A.Chaves-Sanjuan, L.J.Gourlay, M.Tiberi, M.Polentarutti, N.Demitri, G.Bais, M.Nardini. Nuclear Factor One X - Nfix in P41212 To Be Published.