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Atomistry » Zinc » PDB 7q4v-7qno » 7qgx » |
Zinc in PDB 7qgx: Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic AcidEnzymatic activity of Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid
All present enzymatic activity of Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid:
4.2.1.1; Protein crystallography data
The structure of Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid, PDB code: 7qgx
was solved by
V.Paketuryte-Latve,
A.Smirnov,
E.Manakova,
S.Grazulis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7qgx:
The structure of Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid
(pdb code 7qgx). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid, PDB code: 7qgx: Zinc binding site 1 out of 1 in 7qgxGo back to Zinc Binding Sites List in 7qgx
Zinc binding site 1 out
of 1 in the Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid
Mono view Stereo pair view
Reference:
B.Balandis,
T.Simkunas,
V.Paketuryte-Latve,
V.Michailoviene,
A.Mickeviciute,
E.Manakova,
S.Grazulis,
S.Belyakov,
V.Kairys,
V.Mickevicius,
A.Zubriene,
D.Matulis.
Beta and Gamma Amino Acid-Substituted Benzenesulfonamides As Inhibitors of Human Carbonic Anhydrases. Pharmaceuticals V. 15 2022.
Page generated: Wed Oct 30 09:54:08 2024
ISSN: ESSN 1424-8247 PubMed: 35455474 DOI: 10.3390/PH15040477 |
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