Zinc in PDB 7qe7: High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1
Zinc Binding Sites:
The binding sites of Zinc atom in the High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1
(pdb code 7qe7). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the
High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1, PDB code: 7qe7:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
Zinc binding site 1 out
of 6 in 7qe7
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Zinc Binding Sites List in 7qe7
Zinc binding site 1 out
of 6 in the High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
N:Zn901
b:105.0
occ:1.00
|
SG
|
N:CYS224
|
2.2
|
105.4
|
1.0
|
SG
|
N:CYS221
|
2.3
|
87.8
|
1.0
|
SG
|
N:CYS233
|
2.3
|
95.7
|
1.0
|
SG
|
N:CYS231
|
2.3
|
106.0
|
1.0
|
CB
|
N:CYS224
|
2.9
|
88.5
|
1.0
|
CB
|
N:CYS231
|
3.3
|
93.7
|
1.0
|
CB
|
N:CYS221
|
3.4
|
89.5
|
1.0
|
N
|
N:CYS224
|
3.4
|
79.1
|
1.0
|
CA
|
N:CYS224
|
3.7
|
83.8
|
1.0
|
CB
|
N:CYS233
|
3.7
|
83.6
|
1.0
|
CA
|
N:CYS231
|
3.9
|
89.5
|
1.0
|
N
|
N:CYS233
|
4.1
|
80.8
|
1.0
|
N
|
N:TRP232
|
4.3
|
82.8
|
1.0
|
C
|
N:CYS231
|
4.4
|
85.3
|
1.0
|
CA
|
N:CYS233
|
4.5
|
82.1
|
1.0
|
C
|
N:GLY223
|
4.5
|
77.9
|
1.0
|
C
|
N:CYS224
|
4.6
|
82.1
|
1.0
|
CA
|
N:CYS221
|
4.7
|
87.2
|
1.0
|
N
|
N:GLY223
|
4.7
|
77.8
|
1.0
|
C
|
N:CYS221
|
4.9
|
84.2
|
1.0
|
CA
|
N:GLY223
|
4.9
|
76.8
|
1.0
|
N
|
N:SER225
|
5.0
|
80.2
|
1.0
|
|
Zinc binding site 2 out
of 6 in 7qe7
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Zinc Binding Sites List in 7qe7
Zinc binding site 2 out
of 6 in the High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
S:Zn501
b:186.3
occ:1.00
|
SG
|
S:CYS381
|
2.4
|
175.0
|
1.0
|
SG
|
S:CYS396
|
2.4
|
177.5
|
1.0
|
SG
|
S:CYS401
|
2.4
|
164.0
|
1.0
|
SG
|
S:CYS378
|
2.5
|
171.2
|
1.0
|
CB
|
S:CYS381
|
2.7
|
170.7
|
1.0
|
O
|
S:CYS401
|
3.4
|
148.8
|
1.0
|
CB
|
S:CYS396
|
3.4
|
169.1
|
1.0
|
CB
|
S:CYS378
|
3.4
|
170.9
|
1.0
|
N
|
S:CYS381
|
3.5
|
167.7
|
1.0
|
CB
|
S:CYS401
|
3.5
|
152.6
|
1.0
|
CA
|
S:CYS381
|
3.7
|
169.2
|
1.0
|
C
|
S:CYS401
|
4.0
|
150.4
|
1.0
|
CB
|
S:ARG380
|
4.3
|
160.1
|
1.0
|
CA
|
S:CYS401
|
4.5
|
146.3
|
1.0
|
C
|
S:ARG380
|
4.5
|
165.0
|
1.0
|
C
|
S:CYS381
|
4.8
|
169.7
|
1.0
|
CB
|
S:ARG398
|
4.8
|
146.9
|
1.0
|
CA
|
S:ARG380
|
4.8
|
162.4
|
1.0
|
N
|
S:GLY402
|
4.8
|
153.9
|
1.0
|
CA
|
S:CYS396
|
4.9
|
166.4
|
1.0
|
CA
|
S:CYS378
|
4.9
|
170.6
|
1.0
|
N
|
S:PHE403
|
4.9
|
161.8
|
1.0
|
N
|
S:ARG380
|
4.9
|
164.7
|
1.0
|
CA
|
S:GLY402
|
5.0
|
154.7
|
1.0
|
|
Zinc binding site 3 out
of 6 in 7qe7
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Zinc Binding Sites List in 7qe7
Zinc binding site 3 out
of 6 in the High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
S:Zn502
b:208.6
occ:1.00
|
SG
|
S:CYS409
|
2.2
|
175.5
|
1.0
|
NE2
|
S:HIS414
|
2.2
|
206.2
|
1.0
|
SG
|
S:CYS419
|
2.3
|
200.1
|
1.0
|
SG
|
S:CYS406
|
2.4
|
187.7
|
1.0
|
CE1
|
S:HIS414
|
2.4
|
203.2
|
1.0
|
CB
|
S:LYS408
|
3.1
|
169.8
|
1.0
|
CB
|
S:CYS409
|
3.6
|
165.2
|
1.0
|
CB
|
S:CYS419
|
3.6
|
204.6
|
1.0
|
CD2
|
S:HIS414
|
3.6
|
204.3
|
1.0
|
N
|
S:CYS409
|
3.7
|
166.5
|
1.0
|
ND1
|
S:HIS414
|
3.7
|
203.6
|
1.0
|
CG
|
S:LYS408
|
4.0
|
170.7
|
1.0
|
CB
|
S:CYS406
|
4.0
|
183.6
|
1.0
|
C
|
S:LYS408
|
4.1
|
164.4
|
1.0
|
CA
|
S:LYS408
|
4.2
|
165.8
|
1.0
|
CA
|
S:CYS409
|
4.3
|
165.7
|
1.0
|
NZ
|
S:LYS417
|
4.3
|
192.2
|
1.0
|
CG
|
S:HIS414
|
4.3
|
204.0
|
1.0
|
CA
|
S:CYS419
|
4.5
|
207.9
|
1.0
|
N
|
S:LYS408
|
4.7
|
166.4
|
1.0
|
O
|
S:LYS408
|
4.9
|
159.5
|
1.0
|
O
|
S:CYS406
|
4.9
|
171.4
|
1.0
|
|
Zinc binding site 4 out
of 6 in 7qe7
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Zinc Binding Sites List in 7qe7
Zinc binding site 4 out
of 6 in the High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn101
b:191.4
occ:1.00
|
ND1
|
C:HIS56
|
2.0
|
189.7
|
1.0
|
SG
|
C:CYS59
|
2.2
|
189.2
|
1.0
|
SG
|
C:CYS23
|
2.3
|
186.8
|
1.0
|
SG
|
C:CYS26
|
2.3
|
185.5
|
1.0
|
CE1
|
C:HIS56
|
2.8
|
187.6
|
1.0
|
CG
|
C:HIS56
|
3.2
|
190.2
|
1.0
|
CB
|
C:CYS59
|
3.3
|
190.7
|
1.0
|
CB
|
C:CYS23
|
3.3
|
180.2
|
1.0
|
CB
|
C:CYS26
|
3.5
|
181.7
|
1.0
|
CB
|
C:HIS56
|
3.7
|
190.7
|
1.0
|
N
|
C:HIS56
|
3.8
|
190.7
|
1.0
|
N
|
C:CYS26
|
3.8
|
180.8
|
1.0
|
NE2
|
C:HIS56
|
4.0
|
185.8
|
1.0
|
CD2
|
C:HIS56
|
4.2
|
188.6
|
1.0
|
CA
|
C:CYS26
|
4.3
|
180.4
|
1.0
|
CA
|
C:HIS56
|
4.4
|
190.9
|
1.0
|
CB
|
C:ILE25
|
4.6
|
183.1
|
1.0
|
N
|
C:ILE25
|
4.6
|
182.5
|
1.0
|
CA
|
C:CYS59
|
4.7
|
191.2
|
1.0
|
C
|
C:ILE25
|
4.7
|
181.4
|
1.0
|
CB
|
C:PHE55
|
4.7
|
187.7
|
1.0
|
C
|
C:PHE55
|
4.7
|
187.4
|
1.0
|
CA
|
C:CYS23
|
4.7
|
177.3
|
1.0
|
CA
|
C:PHE55
|
4.8
|
187.3
|
1.0
|
CA
|
C:ILE25
|
4.9
|
182.4
|
1.0
|
N
|
C:GLY24
|
4.9
|
179.9
|
1.0
|
|
Zinc binding site 5 out
of 6 in 7qe7
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Zinc Binding Sites List in 7qe7
Zinc binding site 5 out
of 6 in the High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn102
b:212.3
occ:1.00
|
ND1
|
C:HIS58
|
2.2
|
196.2
|
1.0
|
SG
|
C:CYS44
|
2.2
|
199.0
|
1.0
|
CB
|
C:CYS44
|
2.3
|
193.8
|
1.0
|
SG
|
C:CYS34
|
2.3
|
192.7
|
1.0
|
SG
|
C:CYS37
|
2.3
|
195.0
|
1.0
|
CE1
|
C:HIS58
|
2.5
|
193.5
|
1.0
|
CB
|
C:CYS37
|
2.7
|
185.2
|
1.0
|
CG
|
C:HIS58
|
3.5
|
194.9
|
1.0
|
CA
|
C:CYS44
|
3.5
|
191.5
|
1.0
|
NE2
|
C:HIS58
|
3.8
|
191.4
|
1.0
|
CB
|
C:CYS34
|
3.9
|
185.7
|
1.0
|
CA
|
C:CYS37
|
4.2
|
182.8
|
1.0
|
CD2
|
C:HIS58
|
4.2
|
192.8
|
1.0
|
CB
|
C:HIS58
|
4.2
|
193.5
|
1.0
|
N
|
C:CYS44
|
4.3
|
188.6
|
1.0
|
C
|
C:CYS44
|
4.6
|
189.8
|
1.0
|
N
|
C:CYS37
|
4.6
|
186.3
|
1.0
|
O
|
C:ASP43
|
4.7
|
190.1
|
1.0
|
C
|
C:ASP43
|
4.9
|
188.4
|
1.0
|
O
|
C:CYS44
|
4.9
|
187.6
|
1.0
|
|
Zinc binding site 6 out
of 6 in 7qe7
Go back to
Zinc Binding Sites List in 7qe7
Zinc binding site 6 out
of 6 in the High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of High-Resolution Structure of the Anaphase-Promoting Complex/Cyclosome (Apc/C) Bound to Co-Activator CDH1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn103
b:205.4
occ:1.00
|
CB
|
C:CYS51
|
1.9
|
194.1
|
1.0
|
ND1
|
C:HIS53
|
2.1
|
192.6
|
1.0
|
SG
|
C:CYS76
|
2.4
|
196.6
|
1.0
|
SG
|
C:CYS73
|
2.4
|
194.7
|
1.0
|
SG
|
C:CYS51
|
2.4
|
197.7
|
1.0
|
CE1
|
C:HIS53
|
2.7
|
191.3
|
1.0
|
CB
|
C:CYS73
|
3.0
|
191.2
|
1.0
|
CG
|
C:HIS53
|
3.3
|
190.5
|
1.0
|
CA
|
C:CYS51
|
3.4
|
192.9
|
1.0
|
O
|
C:CYS51
|
3.8
|
190.8
|
1.0
|
CB
|
C:CYS76
|
3.8
|
192.4
|
1.0
|
CB
|
C:HIS53
|
3.9
|
190.3
|
1.0
|
N
|
C:CYS76
|
3.9
|
193.1
|
1.0
|
NE2
|
C:HIS53
|
3.9
|
188.5
|
1.0
|
C
|
C:CYS51
|
3.9
|
191.6
|
1.0
|
CB
|
C:MET75
|
4.0
|
189.1
|
1.0
|
CD2
|
C:HIS53
|
4.2
|
188.8
|
1.0
|
N
|
C:CYS51
|
4.4
|
191.5
|
1.0
|
CA
|
C:CYS76
|
4.4
|
192.7
|
1.0
|
CA
|
C:CYS73
|
4.5
|
190.4
|
1.0
|
NE2
|
C:GLN78
|
4.5
|
181.3
|
1.0
|
CZ3
|
C:TRP80
|
4.6
|
189.5
|
1.0
|
CA
|
C:MET75
|
4.7
|
191.4
|
1.0
|
N
|
C:MET75
|
4.7
|
190.2
|
1.0
|
N
|
C:HIS53
|
4.7
|
188.1
|
1.0
|
C
|
C:MET75
|
4.7
|
193.2
|
1.0
|
CG
|
C:MET75
|
4.8
|
189.2
|
1.0
|
C
|
C:CYS73
|
4.9
|
191.2
|
1.0
|
CA
|
C:HIS53
|
4.9
|
188.5
|
1.0
|
|
Reference:
A.Hoefler,
J.Yu,
L.Chang,
Z.Zhang,
J.Yang,
A.Boland,
D.Barford.
High-Resolution Structure of the Anaphase-Promoting Complex (Apc/C) Bound to Co-Activator CDH1 To Be Published.
Page generated: Sat Apr 8 01:54:19 2023
|