Zinc in PDB 7qb0: Solution Structure of Paxillin LIM2/3

The binding sites of Zinc atom in the Solution Structure of Paxillin LIM2/3 (pdb code 7qb0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Solution Structure of Paxillin LIM2/3, PDB code: 7qb0:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Solution Structure of Paxillin LIM2/3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of Paxillin LIM2/3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:53.3 occ:1.00 ND1 A:HIS27 1.9 31.2 1.0 ND1 A:HIS24 2.2 53.1 1.0 SG A:CYS4 2.3 22.1 1.0 SG A:CYS7 2.4 11.1 1.0 HB2 A:HIS24 2.5 51.5 1.0 CE1 A:HIS27 2.5 40.0 1.0 HE1 A:HIS27 2.6 22.1 1.0 HB3 A:CYS7 2.9 22.0 1.0 HB3 A:CYS4 2.9 61.3 1.0 CG A:HIS24 3.1 44.5 1.0 CB A:CYS4 3.1 74.3 1.0 CG A:HIS27 3.1 44.3 1.0 CB A:CYS7 3.2 63.4 1.0 CB A:HIS24 3.2 50.0 1.0 CE1 A:HIS24 3.3 55.1 1.0 HB2 A:CYS4 3.4 30.3 1.0 HB2 A:HIS27 3.5 75.1 1.0 HB3 A:TYR6 3.5 75.3 1.0 H A:CYS7 3.5 60.2 1.0 HE1 A:HIS24 3.6 31.3 1.0 H A:HIS24 3.7 1.2 1.0 NE2 A:HIS27 3.7 63.3 1.0 HB3 A:HIS24 3.8 0.3 1.0 CB A:HIS27 3.8 25.0 1.0 N A:CYS7 3.8 2.5 1.0 HB3 A:HIS27 4.0 62.2 1.0 CD2 A:HIS27 4.0 22.2 1.0 HB2 A:CYS7 4.0 5.1 1.0 CA A:CYS7 4.1 11.0 1.0 CD2 A:HIS24 4.3 41.1 1.0 NE2 A:HIS24 4.3 11.4 1.0 N A:HIS24 4.4 42.1 1.0 CA A:HIS24 4.4 52.5 1.0 H A:GLY9 4.4 1.1 1.0 CA A:CYS4 4.5 71.5 1.0 HE2 A:HIS27 4.5 54.2 1.0 CB A:TYR6 4.5 4.5 1.0 HD1 A:TYR6 4.5 31.2 1.0 C A:TYR6 4.6 71.1 1.0 O A:CYS4 4.7 71.3 1.0 H A:TYR6 4.7 32.5 1.0 C A:CYS4 4.8 54.2 1.0 C A:CYS7 4.8 55.5 1.0 HA A:CYS7 4.9 24.1 1.0 HB2 A:TYR6 5.0 42.2 1.0 HA A:HIS24 5.0 71.2 1.0 CA A:TYR6 5.0 10.3 1.0

Zinc binding site 2 out of 4 in the Solution Structure of Paxillin LIM2/3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of Paxillin LIM2/3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:12.1 occ:1.00 OD1 A:ASP54 2.0 42.1 1.0 SG A:CYS33 2.2 54.0 1.0 SG A:CYS30 2.3 71.5 1.0 SG A:CYS51 2.4 40.2 1.0 H A:CYS51 2.6 43.0 1.0 H A:CYS33 2.7 0.2 1.0 HB2 A:CYS51 2.9 30.4 1.0 HB3 A:CYS30 3.0 53.3 1.0 CB A:CYS30 3.1 75.5 1.0 HB3 A:CYS33 3.1 22.1 1.0 CG A:ASP54 3.1 34.5 1.0 CB A:CYS51 3.2 11.5 1.0 CB A:CYS33 3.2 22.4 1.0 HB2 A:CYS30 3.3 31.4 1.0 N A:CYS51 3.5 70.1 1.0 N A:CYS33 3.5 72.5 1.0 H A:GLY34 3.5 5.3 1.0 HB3 A:GLN32 3.7 52.3 1.0 OD2 A:ASP54 3.8 14.1 1.0 CA A:CYS33 3.9 24.2 1.0 CA A:CYS51 3.9 52.4 1.0 HA A:TYR50 3.9 42.4 1.0 HB2 A:GLN32 4.0 55.3 1.0 HB3 A:CYS51 4.1 14.1 1.0 HB2 A:ASP54 4.1 12.5 1.0 HB2 A:CYS33 4.2 34.2 1.0 N A:GLY34 4.2 75.2 1.0 CB A:ASP54 4.2 34.1 1.0 H A:GLN32 4.2 64.1 1.0 CB A:GLN32 4.3 41.3 1.0 H A:ALA35 4.4 50.2 1.0 C A:CYS33 4.5 60.4 1.0 HA A:CYS51 4.5 2.4 1.0 C A:TYR50 4.5 73.5 1.0 CA A:CYS30 4.5 30.2 1.0 C A:GLN32 4.6 63.1 1.0 H A:ASP54 4.7 72.1 1.0 HB3 A:ASP54 4.7 42.3 1.0 CA A:TYR50 4.7 14.3 1.0 HA A:CYS33 4.8 71.1 1.0 CA A:GLN32 4.8 23.2 1.0 HA A:CYS30 4.9 63.4 1.0 N A:GLN32 4.9 0.2 1.0

Zinc binding site 3 out of 4 in the Solution Structure of Paxillin LIM2/3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Solution Structure of Paxillin LIM2/3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn203 b:43.4 occ:1.00 ND1 A:HIS83 2.0 33.1 1.0 SG A:CYS86 2.3 2.3 1.0 SG A:CYS63 2.3 50.1 1.0 SG A:CYS66 2.5 4.5 1.0 HB2 A:HIS83 2.8 40.3 1.0 HB2 A:CYS63 2.8 42.5 1.0 CE1 A:HIS83 2.9 1.5 1.0 H A:HIS83 2.9 51.1 1.0 HB3 A:CYS66 3.0 15.1 1.0 CG A:HIS83 3.0 14.1 1.0 CB A:CYS63 3.1 2.2 1.0 HE1 A:HIS83 3.1 43.2 1.0 HB2 A:CYS86 3.2 10.2 1.0 CB A:CYS66 3.2 62.5 1.0 CB A:CYS86 3.3 70.3 1.0 CB A:HIS83 3.4 11.5 1.0 HB3 A:CYS86 3.5 45.5 1.0 HB3 A:CYS63 3.5 63.0 1.0 HB2 A:CYS66 3.7 52.0 1.0 N A:HIS83 3.8 63.1 1.0 NE2 A:HIS83 4.0 34.1 1.0 CD2 A:HIS83 4.0 2.3 1.0 H A:ALA67 4.2 13.2 1.0 CA A:HIS83 4.2 72.5 1.0 HB3 A:HIS83 4.2 63.2 1.0 HB3 A:TRP82 4.3 5.5 1.0 CA A:CYS63 4.4 32.3 1.0 HA A:CYS63 4.5 61.4 1.0 HA A:TRP82 4.5 54.0 1.0 CA A:CYS66 4.6 74.2 1.0 CA A:CYS86 4.6 21.4 1.0 HB3 A:ALA67 4.7 32.2 1.0 N A:ALA67 4.7 43.1 1.0 HB2 A:ALA67 4.8 31.0 1.0 H A:CYS86 4.8 51.4 1.0 HA A:CYS86 4.8 33.1 1.0 HG12 A:ILE70 4.9 63.0 1.0 HE2 A:HIS83 4.9 21.4 1.0 C A:TRP82 4.9 30.2 1.0 HD12 A:ILE70 4.9 42.4 1.0 C A:CYS66 5.0 60.2 1.0 HA A:HIS83 5.0 72.1 1.0 HE3 A:TRP82 5.0 52.4 1.0 H A:CYS66 5.0 51.4 1.0

Zinc binding site 4 out of 4 in the Solution Structure of Paxillin LIM2/3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Solution Structure of Paxillin LIM2/3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn204 b:24.2 occ:1.00 ND1 A:HIS113 2.1 43.2 1.0 SG A:CYS92 2.2 41.5 1.0 SG A:CYS89 2.3 53.3 1.0 SG A:CYS110 2.5 34.5 1.0 CE1 A:HIS113 2.7 2.2 1.0 HB2 A:CYS89 2.8 71.0 1.0 HE1 A:HIS113 2.9 34.0 1.0 H A:CYS89 2.9 75.1 1.0 HB2 A:CYS110 2.9 63.3 1.0 CB A:CYS89 3.1 4.2 1.0 CG A:HIS113 3.1 42.1 1.0 HB3 A:CYS92 3.2 34.1 1.0 CB A:CYS110 3.2 53.4 1.0 H A:CYS110 3.3 32.4 1.0 HB2 A:HIS113 3.3 71.3 1.0 CB A:CYS92 3.3 52.4 1.0 CB A:HIS113 3.7 3.2 1.0 N A:CYS89 3.7 62.4 1.0 NE2 A:HIS113 3.8 51.4 1.0 HB2 A:CYS92 3.8 12.5 1.0 HB3 A:CYS89 3.9 30.2 1.0 N A:CYS110 3.9 2.4 1.0 H A:CYS92 3.9 41.1 1.0 HB3 A:HIS113 4.0 32.4 1.0 CD2 A:HIS113 4.0 10.3 1.0 CA A:CYS89 4.0 41.2 1.0 HB3 A:CYS110 4.0 2.1 1.0 CA A:CYS110 4.2 64.5 1.0 O A:THR94 4.3 44.5 1.0 H A:PHE93 4.4 43.5 1.0 HG21 A:THR94 4.5 60.2 1.0 HA A:TYR109 4.5 45.1 1.0 CA A:CYS92 4.5 10.2 1.0 HA A:VAL88 4.6 41.4 1.0 HE2 A:HIS113 4.6 61.4 1.0 N A:CYS92 4.7 10.4 1.0 H A:THR94 4.7 62.2 1.0 HA A:CYS89 4.7 71.2 1.0 HA A:CYS110 4.8 64.2 1.0 H A:HIS113 4.8 1.3 1.0 HB A:VAL88 4.9 54.1 1.0 C A:VAL88 4.9 20.4 1.0 C A:TYR109 4.9 42.5 1.0

T.Baade, M.Michaelis, A.Prestel, C.Paone, N.Klishin, L.Scheinost, R.Nedielkov, C.R.Hauck, H.M.Moeller. A Flexible Loop in the Paxillin LIM3 Domain Mediates Direct Binding to Integrin BETA3 To Be Published.