Zinc in PDB 7pki: Crystal Structure of Human ACE2 Bound to the Spike Receptor-Binding Domain From A Cave Bat Sarbecovirus Closely Related to Sars-Cov-2.

The structure of Crystal Structure of Human ACE2 Bound to the Spike Receptor-Binding Domain From A Cave Bat Sarbecovirus Closely Related to Sars-Cov-2., PDB code: 7pki was solved by E.Baquero, F.A.Rey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.30 / 2.94
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	341.535, 341.535, 68.153, 90, 90, 120
R / Rfree (%)	21.4 / 22.7

The structure of Crystal Structure of Human ACE2 Bound to the Spike Receptor-Binding Domain From A Cave Bat Sarbecovirus Closely Related to Sars-Cov-2. also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Zinc atom in the Crystal Structure of Human ACE2 Bound to the Spike Receptor-Binding Domain From A Cave Bat Sarbecovirus Closely Related to Sars-Cov-2. (pdb code 7pki). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human ACE2 Bound to the Spike Receptor-Binding Domain From A Cave Bat Sarbecovirus Closely Related to Sars-Cov-2., PDB code: 7pki:

Zinc binding site 1 out of 1 in the Crystal Structure of Human ACE2 Bound to the Spike Receptor-Binding Domain From A Cave Bat Sarbecovirus Closely Related to Sars-Cov-2.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human ACE2 Bound to the Spike Receptor-Binding Domain From A Cave Bat Sarbecovirus Closely Related to Sars-Cov-2. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn711 b:65.9 occ:1.00 OH A:TYR515 2.8 67.2 1.0 CZ A:TYR515 3.6 72.0 1.0 O A:HOH801 3.7 38.1 1.0 CE1 A:HIS345 3.7 62.5 1.0 CE1 A:TYR515 3.7 73.0 1.0 NE2 A:HIS505 3.8 59.5 1.0 NH1 A:ARG273 3.9 59.9 1.0 O A:HOH802 4.0 51.3 1.0 OE2 A:GLU375 4.1 55.5 1.0 NE2 A:HIS374 4.2 48.7 1.0 NH2 A:ARG273 4.3 56.2 1.0 CE1 A:HIS505 4.3 61.4 1.0 O A:PRO346 4.3 57.5 1.0 OE2 A:GLU402 4.4 59.8 1.0 OE1 A:GLU402 4.4 61.4 1.0 NE2 A:HIS345 4.5 64.8 1.0 CD2 A:HIS374 4.5 49.2 1.0 CZ A:ARG273 4.6 68.8 1.0 ND1 A:HIS345 4.7 64.6 1.0 CD A:GLU402 4.7 65.7 1.0 CE2 A:TYR515 4.8 64.0 1.0 CD1 A:TYR515 5.0 75.6 1.0

E.Baquero, F.A.Rey. Crystal Structure of Human ACE2 Bound to the Spike Receptor-Binding Domain From A Cave Bat Sarbecovirus Closely Related to Sars-Cov-2. To Be Published.