Zinc in PDB 7pgq: Gap-Secph Region of Human Neurofibromin Isoform 2 in Closed Conformation.

The binding sites of Zinc atom in the Gap-Secph Region of Human Neurofibromin Isoform 2 in Closed Conformation. (pdb code 7pgq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Gap-Secph Region of Human Neurofibromin Isoform 2 in Closed Conformation., PDB code: 7pgq:

Zinc binding site 1 out of 1 in the Gap-Secph Region of Human Neurofibromin Isoform 2 in Closed Conformation.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Gap-Secph Region of Human Neurofibromin Isoform 2 in Closed Conformation. within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn2902 b:162.8 occ:1.00 NE2 F:HIS1558 2.0 136.9 1.0 NE2 F:HIS1576 2.1 150.6 1.0 SG F:CYS1032 2.3 118.2 1.0 CD2 F:HIS1576 2.6 150.6 1.0 CE1 F:HIS1558 2.9 136.9 1.0 HE1 F:HIS1558 2.9 136.9 1.0 CD2 F:HIS1558 3.2 136.9 1.0 CE1 F:HIS1576 3.3 150.6 1.0 HD2 F:HIS1558 3.5 136.9 1.0 HB3 F:CYS1032 3.6 118.2 1.0 CB F:CYS1032 3.6 118.2 1.0 HA F:CYS1032 3.9 118.2 1.0 CG F:HIS1576 3.9 150.6 1.0 ND1 F:HIS1558 4.0 136.9 1.0 ND1 F:HIS1576 4.2 150.6 1.0 CG F:HIS1558 4.2 136.9 1.0 CA F:CYS1032 4.3 118.2 1.0 HB2 F:CYS1032 4.3 118.2 1.0 HE3 F:LYS1581 4.4 159.4 1.0 HZ1 F:LYS1581 4.4 159.4 1.0 HZ F:PHE1572 4.6 149.6 1.0 HG F:SER987 4.7 104.0 1.0 HZ2 F:LYS1581 4.7 159.4 1.0 HD1 F:HIS1558 4.8 136.9 1.0 NZ F:LYS1581 4.9 159.4 1.0 HE2 F:PHE1572 4.9 149.6 1.0

A.Naschberger, R.Baradaran, B.Rupp, M.Carroni. The Structure of Neurofibromin Isoform 2 Reveals Different Functional States. Nature V. 599 315 2021.
ISSN: ESSN 1476-4687
PubMed: 34707296
DOI: 10.1038/S41586-021-04024-X