Zinc in PDB 7pel: Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma
Zinc Binding Sites:
The binding sites of Zinc atom in the Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma
(pdb code 7pel). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the
Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma, PDB code: 7pel:
Jump to Zinc binding site number:
1;
2;
3;
4;
Zinc binding site 1 out
of 4 in 7pel
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Zinc Binding Sites List in 7pel
Zinc binding site 1 out
of 4 in the Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma
 Mono view
 Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1000
b:53.0
occ:1.00
|
ND1
|
A:HIS12
|
2.0
|
28.7
|
1.0
|
NE2
|
A:HIS8
|
2.0
|
29.6
|
1.0
|
CE1
|
A:HIS12
|
2.1
|
28.7
|
1.0
|
SG
|
A:CYS35
|
2.3
|
51.5
|
1.0
|
SG
|
A:CYS38
|
2.3
|
52.1
|
1.0
|
CD2
|
A:HIS8
|
2.7
|
29.6
|
1.0
|
CE1
|
A:HIS8
|
3.0
|
29.6
|
1.0
|
CB
|
A:CYS35
|
3.2
|
51.5
|
1.0
|
CG
|
A:HIS12
|
3.2
|
28.7
|
1.0
|
NE2
|
A:HIS12
|
3.3
|
28.7
|
1.0
|
CD2
|
A:HIS12
|
3.8
|
28.7
|
1.0
|
CG
|
A:HIS8
|
3.8
|
29.6
|
1.0
|
ND1
|
A:HIS8
|
3.9
|
29.6
|
1.0
|
CB
|
A:CYS38
|
4.0
|
52.1
|
1.0
|
CB
|
A:HIS12
|
4.2
|
28.7
|
1.0
|
O
|
A:HIS8
|
4.3
|
29.6
|
1.0
|
CA
|
A:HIS12
|
4.4
|
28.7
|
1.0
|
CA
|
A:CYS35
|
4.6
|
51.5
|
1.0
|
N
|
A:CYS38
|
4.7
|
52.1
|
1.0
|
CA
|
A:CYS38
|
4.9
|
52.1
|
1.0
|
C
|
A:HIS8
|
4.9
|
29.6
|
1.0
|
|
Zinc binding site 2 out
of 4 in 7pel
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Zinc Binding Sites List in 7pel
Zinc binding site 2 out
of 4 in the Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma
 Mono view
 Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn1000
b:23.8
occ:1.00
|
NE2
|
B:HIS8
|
2.0
|
5.9
|
1.0
|
ND1
|
B:HIS12
|
2.0
|
4.2
|
1.0
|
SG
|
B:CYS38
|
2.3
|
6.8
|
1.0
|
SG
|
B:CYS35
|
2.3
|
12.5
|
1.0
|
CE1
|
B:HIS12
|
2.6
|
4.2
|
1.0
|
CE1
|
B:HIS8
|
2.9
|
5.9
|
1.0
|
CD2
|
B:HIS8
|
3.0
|
5.9
|
1.0
|
CG
|
B:HIS12
|
3.3
|
4.2
|
1.0
|
CB
|
B:CYS35
|
3.3
|
12.5
|
1.0
|
CB
|
B:CYS38
|
3.5
|
6.8
|
1.0
|
NE2
|
B:HIS12
|
3.9
|
4.2
|
1.0
|
ND1
|
B:HIS8
|
4.0
|
5.9
|
1.0
|
CB
|
B:HIS12
|
4.0
|
4.2
|
1.0
|
CG
|
B:HIS8
|
4.0
|
5.9
|
1.0
|
CD2
|
B:HIS12
|
4.2
|
4.2
|
1.0
|
N
|
B:CYS38
|
4.2
|
6.8
|
1.0
|
CA
|
B:HIS12
|
4.3
|
4.2
|
1.0
|
CA
|
B:CYS38
|
4.5
|
6.8
|
1.0
|
O
|
B:HIS8
|
4.7
|
5.9
|
1.0
|
CA
|
B:CYS35
|
4.8
|
12.5
|
1.0
|
|
Zinc binding site 3 out
of 4 in 7pel
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Zinc Binding Sites List in 7pel
Zinc binding site 3 out
of 4 in the Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma
 Mono view
 Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn1000
b:53.5
occ:1.00
|
ND1
|
D:HIS12
|
2.0
|
29.0
|
1.0
|
NE2
|
D:HIS8
|
2.0
|
30.1
|
1.0
|
CE1
|
D:HIS12
|
2.1
|
29.0
|
1.0
|
SG
|
D:CYS35
|
2.3
|
52.4
|
1.0
|
SG
|
D:CYS38
|
2.3
|
52.0
|
1.0
|
CD2
|
D:HIS8
|
2.7
|
30.1
|
1.0
|
CE1
|
D:HIS8
|
3.0
|
30.1
|
1.0
|
CB
|
D:CYS35
|
3.2
|
52.4
|
1.0
|
CG
|
D:HIS12
|
3.2
|
29.0
|
1.0
|
NE2
|
D:HIS12
|
3.3
|
29.0
|
1.0
|
CD2
|
D:HIS12
|
3.8
|
29.0
|
1.0
|
CG
|
D:HIS8
|
3.8
|
30.1
|
1.0
|
ND1
|
D:HIS8
|
3.9
|
30.1
|
1.0
|
CB
|
D:CYS38
|
4.0
|
52.0
|
1.0
|
CB
|
D:HIS12
|
4.2
|
29.0
|
1.0
|
O
|
D:HIS8
|
4.3
|
30.1
|
1.0
|
CA
|
D:HIS12
|
4.4
|
29.0
|
1.0
|
CA
|
D:CYS35
|
4.6
|
52.4
|
1.0
|
N
|
D:CYS38
|
4.7
|
52.0
|
1.0
|
CA
|
D:CYS38
|
4.9
|
52.0
|
1.0
|
C
|
D:HIS8
|
4.9
|
30.1
|
1.0
|
|
Zinc binding site 4 out
of 4 in 7pel
Go back to
Zinc Binding Sites List in 7pel
Zinc binding site 4 out
of 4 in the Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma
 Mono view
 Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Cryoem Structure of Simian T-Cell Lymphotropic Virus Intasome in Complex with PP2A Regulatory Subunit B56 Gamma within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn1000
b:24.0
occ:1.00
|
NE2
|
E:HIS8
|
2.0
|
5.8
|
1.0
|
ND1
|
E:HIS12
|
2.0
|
4.0
|
1.0
|
SG
|
E:CYS38
|
2.3
|
7.0
|
1.0
|
SG
|
E:CYS35
|
2.3
|
12.7
|
1.0
|
CE1
|
E:HIS12
|
2.6
|
4.0
|
1.0
|
CE1
|
E:HIS8
|
2.9
|
5.8
|
1.0
|
CD2
|
E:HIS8
|
3.0
|
5.8
|
1.0
|
CG
|
E:HIS12
|
3.3
|
4.0
|
1.0
|
CB
|
E:CYS35
|
3.3
|
12.7
|
1.0
|
CB
|
E:CYS38
|
3.5
|
7.0
|
1.0
|
NE2
|
E:HIS12
|
3.9
|
4.0
|
1.0
|
ND1
|
E:HIS8
|
4.0
|
5.8
|
1.0
|
CB
|
E:HIS12
|
4.0
|
4.0
|
1.0
|
CG
|
E:HIS8
|
4.0
|
5.8
|
1.0
|
CD2
|
E:HIS12
|
4.2
|
4.0
|
1.0
|
N
|
E:CYS38
|
4.2
|
7.0
|
1.0
|
CA
|
E:HIS12
|
4.3
|
4.0
|
1.0
|
CA
|
E:CYS38
|
4.5
|
7.0
|
1.0
|
O
|
E:HIS8
|
4.7
|
5.8
|
1.0
|
CA
|
E:CYS35
|
4.8
|
12.7
|
1.0
|
|
Reference:
M.S.Barski,
J.J.Minnell,
Z.Hodakova,
V.E.Pye,
A.Nans,
P.Cherepanov,
G.N.Maertens.
Cryo-Em Structure of the Deltaretroviral Intasome in Complex with the PP2A Regulatory Subunit B56GAMMA. Nat Commun V. 11 5043 2020.
ISSN: ESSN 2041-1723
PubMed: 33028863
DOI: 10.1038/S41467-020-18874-Y
Page generated: Wed Oct 30 09:09:30 2024
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