Zinc in PDB 7p47: Structure of the E3 Ligase SMC5/NSE2 in Complex with UBC9-Sumo Thioester Mimetic

The structure of Structure of the E3 Ligase SMC5/NSE2 in Complex with UBC9-Sumo Thioester Mimetic, PDB code: 7p47 was solved by J.Lascorz, N.Varejao, D.Reverter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.14 / 3.31
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	71.144, 103.24, 115.616, 90, 90, 90
R / Rfree (%)	23.6 / 29.3

The binding sites of Zinc atom in the Structure of the E3 Ligase SMC5/NSE2 in Complex with UBC9-Sumo Thioester Mimetic (pdb code 7p47). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of the E3 Ligase SMC5/NSE2 in Complex with UBC9-Sumo Thioester Mimetic, PDB code: 7p47:

Zinc binding site 1 out of 1 in the Structure of the E3 Ligase SMC5/NSE2 in Complex with UBC9-Sumo Thioester Mimetic


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the E3 Ligase SMC5/NSE2 in Complex with UBC9-Sumo Thioester Mimetic within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:81.7 occ:1.00 ND1 A:HIS202 2.2 81.6 1.0 SG A:CYS221 2.2 62.3 1.0 SG A:CYS200 2.2 121.3 1.0 SG A:CYS226 2.4 106.0 1.0 CE1 A:HIS202 2.7 82.2 1.0 CB A:CYS221 2.8 91.3 1.0 CB A:CYS200 3.2 96.8 1.0 CB A:CYS226 3.2 92.4 1.0 CG A:HIS202 3.4 81.1 1.0 NE2 A:HIS202 3.9 81.7 1.0 CB A:HIS202 4.1 81.5 1.0 CA A:CYS221 4.3 93.0 1.0 CD2 A:HIS202 4.3 81.0 1.0 CA A:CYS200 4.6 97.3 1.0 CB A:GLN223 4.6 84.2 1.0 CA A:CYS226 4.6 93.3 1.0 N A:CYS200 4.8 100.6 1.0 O A:GLN228 4.8 100.1 1.0 C A:CYS226 4.9 94.6 1.0 C A:CYS221 5.0 92.4 1.0

J.Lascorz, N.Varejao, D.Reverter. Structure of the E3 Ligase SMC5/NSE2 in Complex with UBC9-Sumo Thioester Mimetic To Be Published.