Zinc in PDB 7ori: La Crosse Virus Polymerase at Replication Late-Elongation Stage

All present enzymatic activity of La Crosse Virus Polymerase at Replication Late-Elongation Stage:
2.7.7.48;

The structure of La Crosse Virus Polymerase at Replication Late-Elongation Stage also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the La Crosse Virus Polymerase at Replication Late-Elongation Stage (pdb code 7ori). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the La Crosse Virus Polymerase at Replication Late-Elongation Stage, PDB code: 7ori:

Zinc binding site 1 out of 1 in the La Crosse Virus Polymerase at Replication Late-Elongation Stage


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of La Crosse Virus Polymerase at Replication Late-Elongation Stage within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2301 b:172.6 occ:1.00 NE2 A:HIS2169 1.8 145.2 1.0 OD1 A:ASP2178 1.9 154.7 1.0 SG A:CYS2064 2.3 143.6 1.0 NE2 A:HIS2182 2.3 153.5 1.0 CE1 A:HIS2182 2.5 153.5 1.0 CG A:ASP2178 2.5 154.7 1.0 OD2 A:ASP2178 2.5 154.7 1.0 CE1 A:HIS2169 2.7 145.2 1.0 CB A:CYS2064 2.8 143.6 1.0 CD2 A:HIS2169 2.9 145.2 1.0 CD2 A:HIS2182 3.5 153.5 1.0 ND1 A:HIS2182 3.6 153.5 1.0 CD1 A:ILE2173 3.8 145.3 1.0 ND1 A:HIS2169 3.8 145.2 1.0 CB A:ASP2178 3.9 154.7 1.0 CG A:HIS2169 4.0 145.2 1.0 CD1 A:TYR2181 4.1 153.5 1.0 CG A:HIS2182 4.1 153.5 1.0 CA A:CYS2064 4.2 143.6 1.0 N A:GLY2066 4.3 151.3 1.0 N A:GLU2065 4.4 148.3 1.0 CE1 A:TYR2181 4.5 153.5 1.0 CG1 A:ILE2173 4.5 145.3 1.0 CA A:ASP2178 4.6 154.7 1.0 N A:SER2067 4.6 147.2 1.0 C A:CYS2064 4.6 143.6 1.0 O A:ASP2178 4.7 154.7 1.0 CG A:TYR2181 4.8 153.5 1.0 CA A:GLY2066 4.9 151.3 1.0 O A:SER2067 5.0 147.2 1.0

B.Arragain, Q.Durieux Trouilleton, F.Baudin, J.Provaznik, N.Azevedo, S.Cusack, G.Schoehn, H.Malet. Structural Snapshots of La Crosse Virus Polymerase Reveal the Mechanisms Underlying Peribunyaviridae Replication and Transcription. Nat Commun V. 13 902 2022.
ISSN: ESSN 2041-1723
PubMed: 35173159
DOI: 10.1038/S41467-022-28428-Z