Zinc in PDB 7oky: Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
Enzymatic activity of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
All present enzymatic activity of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure):
2.7.7.6;
Other elements in 7oky:
The structure of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure) also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
(pdb code 7oky). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 9 binding sites of Zinc where determined in the
Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure), PDB code: 7oky:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
Zinc binding site 1 out
of 9 in 7oky
Go back to
Zinc Binding Sites List in 7oky
Zinc binding site 1 out
of 9 in the Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn2002
b:86.0
occ:1.00
|
NE2
|
A:HIS84
|
2.1
|
39.9
|
1.0
|
SG
|
A:CYS74
|
2.3
|
50.4
|
1.0
|
SG
|
A:CYS81
|
2.3
|
45.8
|
1.0
|
SG
|
A:CYS71
|
2.3
|
54.0
|
1.0
|
CD2
|
A:HIS84
|
2.6
|
39.9
|
1.0
|
CB
|
A:CYS71
|
3.0
|
54.0
|
1.0
|
CE1
|
A:HIS84
|
3.3
|
39.9
|
1.0
|
CB
|
A:CYS81
|
3.6
|
45.8
|
1.0
|
CG
|
A:HIS84
|
3.9
|
39.9
|
1.0
|
CB
|
A:CYS74
|
3.9
|
50.4
|
1.0
|
N
|
A:CYS74
|
3.9
|
50.4
|
1.0
|
ND1
|
A:HIS84
|
4.1
|
39.9
|
1.0
|
CA
|
A:CYS81
|
4.3
|
45.8
|
1.0
|
CA
|
A:GLY63
|
4.3
|
47.3
|
1.0
|
CA
|
A:CYS74
|
4.4
|
50.4
|
1.0
|
CA
|
A:CYS71
|
4.5
|
54.0
|
1.0
|
CB
|
A:THR73
|
4.5
|
47.1
|
1.0
|
O
|
A:CYS74
|
4.7
|
50.4
|
1.0
|
N
|
A:GLY83
|
4.7
|
38.1
|
1.0
|
CD
|
A:PRO82
|
4.7
|
37.9
|
1.0
|
N
|
A:GLY63
|
4.7
|
47.3
|
1.0
|
C
|
A:CYS74
|
4.8
|
50.4
|
1.0
|
C
|
A:CYS81
|
4.9
|
45.8
|
1.0
|
CA
|
A:GLY83
|
5.0
|
38.1
|
1.0
|
C
|
A:GLY63
|
5.0
|
47.3
|
1.0
|
N
|
A:THR73
|
5.0
|
47.1
|
1.0
|
C
|
A:THR73
|
5.0
|
47.1
|
1.0
|
N
|
A:PRO82
|
5.0
|
37.9
|
1.0
|
|
Zinc binding site 2 out
of 9 in 7oky
Go back to
Zinc Binding Sites List in 7oky
Zinc binding site 2 out
of 9 in the Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn2003
b:124.6
occ:1.00
|
CB
|
A:CYS184
|
2.1
|
79.7
|
1.0
|
SG
|
A:CYS114
|
2.3
|
69.9
|
1.0
|
SG
|
A:CYS111
|
2.3
|
65.6
|
1.0
|
SG
|
A:CYS184
|
2.3
|
79.7
|
1.0
|
SG
|
A:CYS154
|
2.3
|
76.8
|
1.0
|
CB
|
A:CYS111
|
3.1
|
65.6
|
1.0
|
CB
|
A:CYS154
|
3.2
|
76.8
|
1.0
|
CB
|
A:CYS114
|
3.5
|
69.9
|
1.0
|
CA
|
A:CYS184
|
3.6
|
79.7
|
1.0
|
N
|
A:CYS114
|
4.0
|
69.9
|
1.0
|
N
|
A:CYS184
|
4.2
|
79.7
|
1.0
|
CA
|
A:CYS114
|
4.3
|
69.9
|
1.0
|
C
|
A:CYS184
|
4.3
|
79.7
|
1.0
|
NE2
|
A:GLN188
|
4.4
|
72.2
|
1.0
|
N
|
A:GLY185
|
4.4
|
74.2
|
1.0
|
CA
|
A:CYS111
|
4.5
|
65.6
|
1.0
|
CA
|
A:CYS154
|
4.7
|
76.8
|
1.0
|
C
|
A:CYS114
|
4.9
|
69.9
|
1.0
|
N
|
A:ARG186
|
4.9
|
75.4
|
1.0
|
|
Zinc binding site 3 out
of 9 in 7oky
Go back to
Zinc Binding Sites List in 7oky
Zinc binding site 3 out
of 9 in the Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn2000
b:108.5
occ:1.00
|
SG
|
B:CYS1199
|
2.3
|
49.7
|
1.0
|
SG
|
B:CYS1214
|
2.3
|
52.7
|
1.0
|
SG
|
B:CYS1196
|
2.3
|
45.4
|
1.0
|
SG
|
B:CYS1217
|
2.3
|
64.8
|
1.0
|
CB
|
B:CYS1196
|
2.9
|
45.4
|
1.0
|
CB
|
B:CYS1217
|
3.0
|
64.8
|
1.0
|
CB
|
B:CYS1199
|
3.0
|
49.7
|
1.0
|
CB
|
B:CYS1214
|
3.4
|
52.7
|
1.0
|
N
|
B:CYS1199
|
3.5
|
49.7
|
1.0
|
CA
|
B:CYS1199
|
3.8
|
49.7
|
1.0
|
CA
|
B:CYS1217
|
4.2
|
64.8
|
1.0
|
N
|
B:CYS1217
|
4.3
|
64.8
|
1.0
|
OD1
|
B:ASN1219
|
4.4
|
55.0
|
1.0
|
CA
|
B:CYS1196
|
4.4
|
45.4
|
1.0
|
C
|
B:CYS1199
|
4.6
|
49.7
|
1.0
|
CB
|
B:LEU1198
|
4.6
|
46.0
|
1.0
|
C
|
B:LEU1198
|
4.7
|
46.0
|
1.0
|
N
|
B:GLY1200
|
4.8
|
42.6
|
1.0
|
CA
|
B:CYS1214
|
4.8
|
52.7
|
1.0
|
O
|
B:CYS1214
|
4.9
|
52.7
|
1.0
|
N
|
B:LEU1198
|
5.0
|
46.0
|
1.0
|
CA
|
B:LEU1198
|
5.0
|
46.0
|
1.0
|
|
Zinc binding site 4 out
of 9 in 7oky
Go back to
Zinc Binding Sites List in 7oky
Zinc binding site 4 out
of 9 in the Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn301
b:104.9
occ:1.00
|
SG
|
C:CYS94
|
2.3
|
41.6
|
1.0
|
SG
|
C:CYS90
|
2.3
|
55.4
|
1.0
|
SG
|
C:CYS88
|
2.3
|
49.6
|
1.0
|
SG
|
C:CYS97
|
2.3
|
37.0
|
1.0
|
CB
|
C:CYS97
|
3.2
|
37.0
|
1.0
|
CB
|
C:CYS90
|
3.2
|
55.4
|
1.0
|
CB
|
C:CYS88
|
3.2
|
49.6
|
1.0
|
CB
|
C:CYS94
|
3.7
|
41.6
|
1.0
|
N
|
C:CYS94
|
3.8
|
41.6
|
1.0
|
N
|
C:CYS97
|
3.9
|
37.0
|
1.0
|
CA
|
C:CYS97
|
4.2
|
37.0
|
1.0
|
N
|
C:CYS90
|
4.2
|
55.4
|
1.0
|
CA
|
C:CYS94
|
4.2
|
41.6
|
1.0
|
CA
|
C:CYS90
|
4.3
|
55.4
|
1.0
|
NZ
|
Z:LYS718
|
4.3
|
52.4
|
1.0
|
C
|
C:PHE93
|
4.4
|
38.4
|
1.0
|
O
|
C:CYS94
|
4.4
|
41.6
|
1.0
|
CA
|
C:CYS88
|
4.6
|
49.6
|
1.0
|
CA
|
C:PHE93
|
4.6
|
38.4
|
1.0
|
C
|
C:GLU96
|
4.6
|
40.2
|
1.0
|
C
|
C:CYS94
|
4.6
|
41.6
|
1.0
|
CB
|
C:GLU96
|
4.7
|
40.2
|
1.0
|
C
|
C:CYS88
|
4.9
|
49.6
|
1.0
|
|
Zinc binding site 5 out
of 9 in 7oky
Go back to
Zinc Binding Sites List in 7oky
Zinc binding site 5 out
of 9 in the Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Zn201
b:126.8
occ:1.00
|
SG
|
I:CYS119
|
2.3
|
64.0
|
1.0
|
SG
|
I:CYS86
|
2.3
|
62.4
|
1.0
|
SG
|
I:CYS89
|
2.3
|
69.0
|
1.0
|
SG
|
I:CYS114
|
2.3
|
51.3
|
1.0
|
CB
|
I:CYS86
|
3.1
|
62.4
|
1.0
|
CB
|
I:CYS114
|
3.1
|
51.3
|
1.0
|
CB
|
I:CYS119
|
3.4
|
64.0
|
1.0
|
CB
|
I:CYS89
|
3.6
|
69.0
|
1.0
|
N
|
I:CYS89
|
3.9
|
69.0
|
1.0
|
CB
|
I:HIS91
|
4.2
|
61.3
|
1.0
|
CA
|
I:CYS89
|
4.3
|
69.0
|
1.0
|
CB
|
I:HIS121
|
4.4
|
54.4
|
1.0
|
CA
|
I:CYS86
|
4.6
|
62.4
|
1.0
|
CB
|
I:ALA116
|
4.6
|
57.2
|
1.0
|
CA
|
I:CYS114
|
4.6
|
51.3
|
1.0
|
N
|
I:HIS91
|
4.6
|
61.3
|
1.0
|
CB
|
I:LYS88
|
4.8
|
63.6
|
1.0
|
C
|
I:CYS89
|
4.8
|
69.0
|
1.0
|
CA
|
I:CYS119
|
4.8
|
64.0
|
1.0
|
N
|
I:GLY90
|
4.8
|
62.6
|
1.0
|
N
|
I:HIS121
|
4.9
|
54.4
|
1.0
|
|
Zinc binding site 6 out
of 9 in 7oky
Go back to
Zinc Binding Sites List in 7oky
Zinc binding site 6 out
of 9 in the Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Zn202
b:78.9
occ:1.00
|
CB
|
I:CYS20
|
1.9
|
34.2
|
1.0
|
CB
|
I:CYS42
|
2.2
|
49.8
|
1.0
|
SG
|
I:CYS39
|
2.3
|
45.5
|
1.0
|
SG
|
I:CYS17
|
2.4
|
35.1
|
1.0
|
SG
|
I:CYS42
|
2.4
|
49.8
|
1.0
|
SG
|
I:CYS20
|
2.4
|
34.2
|
1.0
|
CB
|
I:CYS39
|
3.3
|
45.5
|
1.0
|
CA
|
I:CYS20
|
3.3
|
34.2
|
1.0
|
CB
|
I:CYS17
|
3.4
|
35.1
|
1.0
|
CA
|
I:CYS42
|
3.7
|
49.8
|
1.0
|
N
|
I:CYS20
|
3.8
|
34.2
|
1.0
|
C
|
I:CYS20
|
4.1
|
34.2
|
1.0
|
N
|
I:CYS42
|
4.2
|
49.8
|
1.0
|
OD1
|
I:ASN41
|
4.3
|
45.7
|
1.0
|
N
|
I:ASN21
|
4.3
|
30.1
|
1.0
|
C
|
I:CYS42
|
4.6
|
49.8
|
1.0
|
C
|
I:GLU19
|
4.7
|
35.0
|
1.0
|
N
|
I:ASP43
|
4.7
|
50.3
|
1.0
|
CA
|
I:CYS39
|
4.7
|
45.5
|
1.0
|
CB
|
I:TYR44
|
4.8
|
47.0
|
1.0
|
N
|
I:ASN22
|
4.8
|
32.4
|
1.0
|
O
|
I:CYS20
|
4.8
|
34.2
|
1.0
|
CA
|
I:CYS17
|
4.9
|
35.1
|
1.0
|
N
|
I:TYR44
|
4.9
|
47.0
|
1.0
|
|
Zinc binding site 7 out
of 9 in 7oky
Go back to
Zinc Binding Sites List in 7oky
Zinc binding site 7 out
of 9 in the Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Zn101
b:57.4
occ:1.00
|
SG
|
J:CYS10
|
2.3
|
15.2
|
1.0
|
SG
|
J:CYS45
|
2.3
|
21.8
|
1.0
|
SG
|
J:CYS44
|
2.3
|
20.3
|
1.0
|
SG
|
J:CYS7
|
2.3
|
15.2
|
1.0
|
CB
|
J:CYS7
|
3.2
|
15.2
|
1.0
|
N
|
J:CYS45
|
3.3
|
21.8
|
1.0
|
CB
|
J:CYS10
|
3.4
|
15.2
|
1.0
|
CB
|
J:CYS45
|
3.6
|
21.8
|
1.0
|
CB
|
J:CYS44
|
3.6
|
20.3
|
1.0
|
CA
|
J:CYS45
|
3.6
|
21.8
|
1.0
|
C
|
J:CYS44
|
3.6
|
20.3
|
1.0
|
N
|
J:CYS10
|
3.9
|
15.2
|
1.0
|
O
|
J:CYS44
|
4.1
|
20.3
|
1.0
|
CA
|
J:CYS44
|
4.2
|
20.3
|
1.0
|
NE
|
J:ARG42
|
4.2
|
23.2
|
1.0
|
CA
|
J:CYS10
|
4.3
|
15.2
|
1.0
|
NH2
|
J:ARG42
|
4.5
|
23.2
|
1.0
|
CB
|
J:LYS12
|
4.6
|
15.4
|
1.0
|
CB
|
J:THR9
|
4.6
|
14.6
|
1.0
|
CA
|
J:CYS7
|
4.7
|
15.2
|
1.0
|
N
|
J:GLY11
|
4.8
|
16.1
|
1.0
|
N
|
J:LYS12
|
4.8
|
15.4
|
1.0
|
CB
|
J:ARG42
|
4.9
|
23.2
|
1.0
|
CZ
|
J:ARG42
|
4.9
|
23.2
|
1.0
|
N
|
J:CYS44
|
4.9
|
20.3
|
1.0
|
C
|
J:CYS10
|
4.9
|
15.2
|
1.0
|
C
|
J:THR9
|
4.9
|
14.6
|
1.0
|
|
Zinc binding site 8 out
of 9 in 7oky
Go back to
Zinc Binding Sites List in 7oky
Zinc binding site 8 out
of 9 in the Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
L:Zn101
b:98.8
occ:1.00
|
SG
|
L:CYS22
|
2.3
|
53.1
|
1.0
|
SG
|
L:CYS36
|
2.3
|
57.0
|
1.0
|
SG
|
L:CYS19
|
2.3
|
49.5
|
1.0
|
SG
|
L:CYS39
|
2.3
|
56.2
|
1.0
|
CB
|
L:CYS36
|
3.1
|
57.0
|
1.0
|
CB
|
L:CYS19
|
3.1
|
49.5
|
1.0
|
CB
|
L:CYS22
|
3.3
|
53.1
|
1.0
|
CB
|
L:CYS39
|
3.8
|
56.2
|
1.0
|
N
|
L:CYS22
|
4.0
|
53.1
|
1.0
|
N
|
L:CYS39
|
4.0
|
56.2
|
1.0
|
OG1
|
L:THR24
|
4.2
|
52.0
|
1.0
|
CA
|
L:CYS22
|
4.2
|
53.1
|
1.0
|
CA
|
L:CYS39
|
4.4
|
56.2
|
1.0
|
CB
|
L:TYR41
|
4.4
|
43.0
|
1.0
|
CA
|
L:CYS36
|
4.5
|
57.0
|
1.0
|
CA
|
L:CYS19
|
4.6
|
49.5
|
1.0
|
N
|
L:TYR41
|
4.7
|
43.0
|
1.0
|
CG
|
L:GLU21
|
4.7
|
52.0
|
1.0
|
N
|
L:GLY40
|
4.8
|
48.8
|
1.0
|
C
|
L:CYS22
|
4.9
|
53.1
|
1.0
|
C
|
L:CYS39
|
4.9
|
56.2
|
1.0
|
CB
|
L:GLU38
|
4.9
|
59.6
|
1.0
|
O
|
L:TYR41
|
4.9
|
43.0
|
1.0
|
N
|
L:HIS23
|
5.0
|
51.0
|
1.0
|
|
Zinc binding site 9 out
of 9 in 7oky
Go back to
Zinc Binding Sites List in 7oky
Zinc binding site 9 out
of 9 in the Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2- EAF1(Composite Structure) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
Y:Zn201
b:15.0
occ:1.00
|
SG
|
Y:CYS19
|
2.3
|
12.8
|
1.0
|
SG
|
Y:CYS33
|
2.3
|
15.0
|
1.0
|
SG
|
Y:CYS36
|
2.3
|
15.8
|
1.0
|
SG
|
Y:CYS16
|
2.3
|
13.4
|
1.0
|
CB
|
Y:CYS19
|
3.1
|
13.5
|
1.0
|
CB
|
Y:CYS36
|
3.1
|
17.6
|
1.0
|
CB
|
Y:CYS16
|
3.3
|
12.9
|
1.0
|
N
|
Y:CYS19
|
3.4
|
13.8
|
1.0
|
CA
|
Y:CYS19
|
3.8
|
13.3
|
1.0
|
N
|
Y:CYS36
|
3.8
|
17.1
|
1.0
|
CB
|
Y:CYS33
|
3.8
|
14.3
|
1.0
|
CA
|
Y:CYS36
|
4.1
|
17.9
|
1.0
|
CB
|
Y:ASN35
|
4.2
|
16.0
|
1.0
|
CB
|
Y:LEU18
|
4.4
|
14.5
|
1.0
|
C
|
Y:CYS19
|
4.5
|
12.8
|
1.0
|
C
|
Y:LEU18
|
4.5
|
14.6
|
1.0
|
C
|
Y:ASN35
|
4.6
|
16.9
|
1.0
|
CB
|
Y:LEU21
|
4.7
|
10.9
|
1.0
|
CA
|
Y:CYS16
|
4.7
|
12.4
|
1.0
|
N
|
Y:SER20
|
4.8
|
11.4
|
1.0
|
CA
|
Y:LEU18
|
4.8
|
14.2
|
1.0
|
N
|
Y:LEU18
|
4.9
|
14.1
|
1.0
|
CA
|
Y:ASN35
|
4.9
|
16.0
|
1.0
|
N
|
Y:LEU21
|
4.9
|
9.9
|
1.0
|
|
Reference:
Y.Chen,
S.M.Vos,
C.Dienemann,
M.Ninov,
H.Urlaub,
P.Cramer.
Structure of Active Transcription Elongation Complex Pol II-Dsif-ELL2-EAF1(Composite Structure) To Be Published.
Page generated: Wed Oct 30 08:34:18 2024
|