Zinc in PDB 7okx: Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure)

Enzymatic activity of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure)

All present enzymatic activity of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure):
2.7.7.6;

Other elements in 7okx:

The structure of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure) also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure) (pdb code 7okx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure), PDB code: 7okx:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Zinc binding site 1 out of 8 in 7okx

Go back to Zinc Binding Sites List in 7okx
Zinc binding site 1 out of 8 in the Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2002

b:86.0
occ:1.00
NE2 A:HIS84 2.1 39.9 1.0
SG A:CYS81 2.3 45.8 1.0
SG A:CYS74 2.3 50.4 1.0
SG A:CYS71 2.3 54.0 1.0
CD2 A:HIS84 2.6 39.9 1.0
CB A:CYS71 3.0 54.0 1.0
CE1 A:HIS84 3.3 39.9 1.0
CB A:CYS81 3.6 45.8 1.0
CG A:HIS84 3.9 39.9 1.0
CB A:CYS74 3.9 50.4 1.0
N A:CYS74 3.9 50.4 1.0
ND1 A:HIS84 4.1 39.9 1.0
CA A:CYS81 4.3 45.8 1.0
CA A:GLY63 4.3 47.3 1.0
CA A:CYS74 4.4 50.4 1.0
CA A:CYS71 4.5 54.0 1.0
CB A:THR73 4.5 47.1 1.0
O A:CYS74 4.7 50.4 1.0
N A:GLY83 4.7 38.1 1.0
CD A:PRO82 4.7 37.9 1.0
N A:GLY63 4.7 47.3 1.0
C A:CYS74 4.8 50.4 1.0
C A:CYS81 4.9 45.8 1.0
CA A:GLY83 5.0 38.1 1.0
C A:GLY63 5.0 47.3 1.0
N A:THR73 5.0 47.1 1.0
C A:THR73 5.0 47.1 1.0
N A:PRO82 5.0 37.9 1.0

Zinc binding site 2 out of 8 in 7okx

Go back to Zinc Binding Sites List in 7okx
Zinc binding site 2 out of 8 in the Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2003

b:124.6
occ:1.00
CB A:CYS184 2.1 79.7 1.0
SG A:CYS114 2.3 69.9 1.0
SG A:CYS111 2.3 65.6 1.0
SG A:CYS154 2.3 76.8 1.0
SG A:CYS184 2.3 79.7 1.0
CB A:CYS111 3.1 65.6 1.0
CB A:CYS154 3.2 76.8 1.0
CB A:CYS114 3.5 69.9 1.0
CA A:CYS184 3.6 79.7 1.0
N A:CYS114 4.0 69.9 1.0
N A:CYS184 4.2 79.7 1.0
CA A:CYS114 4.3 69.9 1.0
C A:CYS184 4.3 79.7 1.0
NE2 A:GLN188 4.4 72.2 1.0
N A:GLY185 4.4 74.2 1.0
CA A:CYS111 4.5 65.6 1.0
CA A:CYS154 4.7 76.8 1.0
C A:CYS114 4.9 69.9 1.0
N A:ARG186 4.9 75.4 1.0

Zinc binding site 3 out of 8 in 7okx

Go back to Zinc Binding Sites List in 7okx
Zinc binding site 3 out of 8 in the Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn2000

b:108.5
occ:1.00
SG B:CYS1199 2.3 49.7 1.0
SG B:CYS1214 2.3 52.7 1.0
SG B:CYS1196 2.3 45.4 1.0
SG B:CYS1217 2.3 64.8 1.0
CB B:CYS1196 2.9 45.4 1.0
CB B:CYS1217 3.0 64.8 1.0
CB B:CYS1199 3.0 49.7 1.0
CB B:CYS1214 3.4 52.7 1.0
N B:CYS1199 3.5 49.7 1.0
CA B:CYS1199 3.8 49.7 1.0
CA B:CYS1217 4.2 64.8 1.0
N B:CYS1217 4.3 64.8 1.0
OD1 B:ASN1219 4.4 55.0 1.0
CA B:CYS1196 4.4 45.4 1.0
C B:CYS1199 4.6 49.7 1.0
CB B:LEU1198 4.6 46.0 1.0
C B:LEU1198 4.7 46.0 1.0
N B:GLY1200 4.8 42.6 1.0
CA B:CYS1214 4.8 52.7 1.0
O B:CYS1214 4.9 52.7 1.0
N B:LEU1198 5.0 46.0 1.0
CA B:LEU1198 5.0 46.0 1.0

Zinc binding site 4 out of 8 in 7okx

Go back to Zinc Binding Sites List in 7okx
Zinc binding site 4 out of 8 in the Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure) within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn301

b:104.9
occ:1.00
SG C:CYS94 2.3 41.6 1.0
SG C:CYS90 2.3 55.4 1.0
SG C:CYS88 2.3 49.6 1.0
SG C:CYS97 2.3 37.0 1.0
CB C:CYS97 3.2 37.0 1.0
CB C:CYS90 3.2 55.4 1.0
CB C:CYS88 3.2 49.6 1.0
CB C:CYS94 3.7 41.6 1.0
N C:CYS94 3.8 41.6 1.0
N C:CYS97 3.9 37.0 1.0
CA C:CYS97 4.2 37.0 1.0
NZ Z:LYS718 4.2 52.4 1.0
N C:CYS90 4.2 55.4 1.0
CA C:CYS94 4.2 41.6 1.0
CA C:CYS90 4.3 55.4 1.0
C C:PHE93 4.4 38.4 1.0
O C:CYS94 4.4 41.6 1.0
CA C:CYS88 4.6 49.6 1.0
CA C:PHE93 4.6 38.4 1.0
C C:GLU96 4.6 40.2 1.0
C C:CYS94 4.6 41.6 1.0
CB C:GLU96 4.7 40.2 1.0
C C:CYS88 4.9 49.6 1.0

Zinc binding site 5 out of 8 in 7okx

Go back to Zinc Binding Sites List in 7okx
Zinc binding site 5 out of 8 in the Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure) within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Zn201

b:126.8
occ:1.00
SG I:CYS119 2.3 64.0 1.0
SG I:CYS89 2.3 69.0 1.0
SG I:CYS86 2.3 62.4 1.0
SG I:CYS114 2.3 51.3 1.0
CB I:CYS86 3.1 62.4 1.0
CB I:CYS114 3.1 51.3 1.0
CB I:CYS119 3.4 64.0 1.0
CB I:CYS89 3.6 69.0 1.0
N I:CYS89 3.9 69.0 1.0
CB I:HIS91 4.2 61.3 1.0
CA I:CYS89 4.3 69.0 1.0
CB I:HIS121 4.4 54.4 1.0
CA I:CYS86 4.6 62.4 1.0
CB I:ALA116 4.6 57.2 1.0
CA I:CYS114 4.6 51.3 1.0
N I:HIS91 4.6 61.3 1.0
CB I:LYS88 4.8 63.6 1.0
C I:CYS89 4.8 69.0 1.0
CA I:CYS119 4.8 64.0 1.0
N I:GLY90 4.8 62.6 1.0
N I:HIS121 4.9 54.4 1.0

Zinc binding site 6 out of 8 in 7okx

Go back to Zinc Binding Sites List in 7okx
Zinc binding site 6 out of 8 in the Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure) within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Zn202

b:78.9
occ:1.00
CB I:CYS20 1.9 34.2 1.0
CB I:CYS42 2.2 49.8 1.0
SG I:CYS39 2.3 45.5 1.0
SG I:CYS17 2.4 35.1 1.0
SG I:CYS42 2.4 49.8 1.0
SG I:CYS20 2.4 34.2 1.0
CB I:CYS39 3.3 45.5 1.0
CA I:CYS20 3.3 34.2 1.0
CB I:CYS17 3.4 35.1 1.0
CA I:CYS42 3.7 49.8 1.0
N I:CYS20 3.8 34.2 1.0
C I:CYS20 4.1 34.2 1.0
N I:CYS42 4.2 49.8 1.0
OD1 I:ASN41 4.3 45.7 1.0
N I:ASN21 4.3 30.1 1.0
C I:CYS42 4.6 49.8 1.0
C I:GLU19 4.7 35.0 1.0
N I:ASP43 4.7 50.3 1.0
CA I:CYS39 4.7 45.5 1.0
CB I:TYR44 4.8 47.0 1.0
N I:ASN22 4.8 32.4 1.0
O I:CYS20 4.8 34.2 1.0
CA I:CYS17 4.9 35.1 1.0
N I:TYR44 4.9 47.0 1.0

Zinc binding site 7 out of 8 in 7okx

Go back to Zinc Binding Sites List in 7okx
Zinc binding site 7 out of 8 in the Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure) within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn101

b:57.4
occ:1.00
SG J:CYS10 2.3 15.2 1.0
SG J:CYS45 2.3 21.8 1.0
SG J:CYS44 2.3 20.3 1.0
SG J:CYS7 2.3 15.2 1.0
CB J:CYS7 3.2 15.2 1.0
N J:CYS45 3.3 21.8 1.0
CB J:CYS10 3.4 15.2 1.0
CB J:CYS45 3.6 21.8 1.0
CB J:CYS44 3.6 20.3 1.0
CA J:CYS45 3.6 21.8 1.0
C J:CYS44 3.6 20.3 1.0
N J:CYS10 3.9 15.2 1.0
O J:CYS44 4.1 20.3 1.0
CA J:CYS44 4.2 20.3 1.0
NE J:ARG42 4.2 23.2 1.0
CA J:CYS10 4.3 15.2 1.0
NH2 J:ARG42 4.5 23.2 1.0
CB J:LYS12 4.6 15.4 1.0
CB J:THR9 4.6 14.6 1.0
CA J:CYS7 4.7 15.2 1.0
N J:GLY11 4.8 16.1 1.0
N J:LYS12 4.8 15.4 1.0
CB J:ARG42 4.9 23.2 1.0
CZ J:ARG42 4.9 23.2 1.0
N J:CYS44 4.9 20.3 1.0
C J:CYS10 4.9 15.2 1.0
C J:THR9 4.9 14.6 1.0

Zinc binding site 8 out of 8 in 7okx

Go back to Zinc Binding Sites List in 7okx
Zinc binding site 8 out of 8 in the Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Structure of Active Transcription Elongation Complex Pol II-Dsif (SPT5-KOW5)-ELL2-EAF1 (Composite Structure) within 5.0Å range:
probe atom residue distance (Å) B Occ
L:Zn101

b:98.8
occ:1.00
SG L:CYS22 2.3 53.1 1.0
SG L:CYS36 2.3 57.0 1.0
SG L:CYS19 2.3 49.5 1.0
SG L:CYS39 2.3 56.2 1.0
CB L:CYS36 3.1 57.0 1.0
CB L:CYS19 3.1 49.5 1.0
CB L:CYS22 3.3 53.1 1.0
CB L:CYS39 3.8 56.2 1.0
N L:CYS22 4.0 53.1 1.0
N L:CYS39 4.0 56.2 1.0
OG1 L:THR24 4.2 52.0 1.0
CA L:CYS22 4.2 53.1 1.0
CA L:CYS39 4.4 56.2 1.0
CB L:TYR41 4.4 43.0 1.0
CA L:CYS36 4.5 57.0 1.0
CA L:CYS19 4.6 49.5 1.0
N L:TYR41 4.7 43.0 1.0
CG L:GLU21 4.7 52.0 1.0
N L:GLY40 4.8 48.8 1.0
C L:CYS22 4.9 53.1 1.0
C L:CYS39 4.9 56.2 1.0
CB L:GLU38 4.9 59.6 1.0
O L:TYR41 4.9 43.0 1.0
N L:HIS23 5.0 51.0 1.0

Reference:

Y.Chen, S.M.Vos, C.Dienemann, M.Ninov, H.Urlaub, P.Cramer. Allosteric Transcription Stimulation By Rna Polymerase II Super Elongation Complex To Be Published.
Page generated: Sun Aug 22 09:53:12 2021

Last articles

Zn in 7RE3
Zn in 7RDX
Zn in 7RDZ
Zn in 7RWM
Zn in 7PGU
Zn in 7PGR
Zn in 7PGT
Zn in 7PGS
Zn in 7SQE
Zn in 7RWK
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy