Zinc in PDB 7o3c: Murine Supercomplex CIII2CIV in the Mature Unlocked Conformation

All present enzymatic activity of Murine Supercomplex CIII2CIV in the Mature Unlocked Conformation:
7.1.1.8; 7.1.1.9;

The structure of Murine Supercomplex CIII2CIV in the Mature Unlocked Conformation also contains other interesting chemical elements:

Sodium	(Na)	1 atom
Iron	(Fe)	12 atoms
Copper	(Cu)	3 atoms
Magnesium	(Mg)	1 atom

The binding sites of Zinc atom in the Murine Supercomplex CIII2CIV in the Mature Unlocked Conformation (pdb code 7o3c). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Murine Supercomplex CIII2CIV in the Mature Unlocked Conformation, PDB code: 7o3c:

Zinc binding site 1 out of 1 in the Murine Supercomplex CIII2CIV in the Mature Unlocked Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Murine Supercomplex CIII2CIV in the Mature Unlocked Conformation within 5.0Å range: probe atom residue distance (Å) B Occ f:Zn100 b:153.1 occ:1.00 CB f:CYS63 2.2 159.1 1.0 SG f:CYS86 2.2 135.5 1.0 SG f:CYS63 2.3 147.2 1.0 SG f:CYS61 2.4 127.7 1.0 SG f:CYS83 2.4 142.1 1.0 CB f:CYS83 3.0 88.8 1.0 CB f:CYS61 3.2 113.7 1.0 CB f:CYS86 3.2 124.5 1.0 CA f:CYS63 3.6 149.6 1.0 OG1 f:THR88 3.7 122.0 1.0 OD1 f:ASN85 3.8 91.7 1.0 N f:CYS63 4.1 148.8 1.0 O f:CYS61 4.4 135.3 1.0 CA f:CYS86 4.4 120.6 1.0 N f:CYS86 4.4 112.8 1.0 CA f:CYS61 4.4 111.9 1.0 CA f:CYS83 4.4 81.5 1.0 C f:CYS61 4.5 127.8 1.0 CG2 f:THR88 4.6 121.3 1.0 C f:CYS63 4.7 139.6 1.0 CB f:THR88 4.8 123.2 1.0 N f:GLY87 4.8 121.6 1.0 CG f:ASN85 4.9 90.3 1.0 C f:CYS83 4.9 90.0 1.0 CG1 f:ILE71 5.0 61.5 1.0 N f:THR88 5.0 124.6 1.0

I.Vercellino, L.A.Sazanov. Structure and Assembly of the Mammalian Mitochondrial Supercomplex CIII2CIV Nature 2021.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-021-03927-Z