Zinc in PDB 7ns4: Catalytic Module of Yeast Chelator-Gid SR4 E3 Ubiquitin Ligase

All present enzymatic activity of Catalytic Module of Yeast Chelator-Gid SR4 E3 Ubiquitin Ligase:
2.3.2.27;

The binding sites of Zinc atom in the Catalytic Module of Yeast Chelator-Gid SR4 E3 Ubiquitin Ligase (pdb code 7ns4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Catalytic Module of Yeast Chelator-Gid SR4 E3 Ubiquitin Ligase, PDB code: 7ns4:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Catalytic Module of Yeast Chelator-Gid SR4 E3 Ubiquitin Ligase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Catalytic Module of Yeast Chelator-Gid SR4 E3 Ubiquitin Ligase within 5.0Å range: probe atom residue distance (Å) B Occ b:Zn501 b:79.5 occ:1.00 NE2 b:HIS381 2.0 45.7 1.0 SG b:CYS404 2.3 70.8 1.0 SG b:CYS379 2.3 52.5 1.0 SG b:CYS401 2.3 47.4 1.0 CD2 b:HIS381 2.4 45.7 1.0 O b:CYS404 3.0 70.8 1.0 CB b:CYS404 3.3 70.8 1.0 CE1 b:HIS381 3.3 45.7 1.0 CB b:CYS401 3.4 47.4 1.0 CB b:CYS379 3.7 52.5 1.0 CG b:HIS381 3.7 45.7 1.0 C b:CYS404 4.0 70.8 1.0 ND1 b:HIS381 4.1 45.7 1.0 CA b:CYS404 4.2 70.8 1.0 O b:CYS379 4.4 52.5 1.0 CA b:CYS401 4.9 47.4 1.0 CA b:CYS379 4.9 52.5 1.0 N b:CYS404 4.9 70.8 1.0

Zinc binding site 2 out of 2 in the Catalytic Module of Yeast Chelator-Gid SR4 E3 Ubiquitin Ligase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Catalytic Module of Yeast Chelator-Gid SR4 E3 Ubiquitin Ligase within 5.0Å range: probe atom residue distance (Å) B Occ i:Zn601 b:32.8 occ:1.00 NE2 b:HIS356 2.0 30.9 1.0 SG i:CYS434 2.3 21.3 1.0 SG i:CYS395 2.3 31.9 1.0 SG i:CYS437 2.3 20.1 1.0 CD2 b:HIS356 2.5 30.9 1.0 CB i:CYS395 3.1 31.9 1.0 CB i:CYS434 3.1 21.3 1.0 CE1 b:HIS356 3.3 30.9 1.0 CA i:CYS395 3.6 31.9 1.0 CG1 i:VAL436 3.7 18.9 1.0 CG b:HIS356 3.8 30.9 1.0 CB i:CYS437 3.9 20.1 1.0 ND1 b:HIS356 4.1 30.9 1.0 N i:CYS437 4.4 20.1 1.0 O i:CYS395 4.5 31.9 1.0 O i:ASP394 4.5 31.4 1.0 CA i:CYS434 4.6 21.3 1.0 C i:CYS395 4.6 31.9 1.0 N i:CYS395 4.6 31.9 1.0 CA i:CYS437 4.8 20.1 1.0 CG2 i:THR392 4.8 25.6 1.0 C i:ASP394 5.0 31.4 1.0

D.Sherpa, J.Chrustowicz, S.Qiao, C.R.Langlois, L.A.Hehl, K.V.Gottemukkala, F.M.Hansen, O.Karayel, J.R.Prabu, M.Mann, A.F.Alpi, B.A.Schulman. Gid E3 Ligase Supramolecular Chelate Assembly Configures Multipronged Ubiquitin Targeting of An Oligomeric Metabolic Enzyme Mol.Cell 2021.
ISSN: ISSN 1097-2765
DOI: 10.1016/J.MOLCEL.2021.03.025