Zinc in PDB 7l97: Crystal Structure of STAMBPL1 in Complex with An Engineered Binder

The structure of Crystal Structure of STAMBPL1 in Complex with An Engineered Binder, PDB code: 7l97 was solved by Y.Guo, A.Dong, F.Hou, Y.Li, W.Zhang, C.H.Arrowsmith, A.M.Edwards, Y.Tong, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.01
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	63.709, 68.882, 57.329, 90, 98.51, 90
R / Rfree (%)	18.5 / 21.4

The binding sites of Zinc atom in the Crystal Structure of STAMBPL1 in Complex with An Engineered Binder (pdb code 7l97). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of STAMBPL1 in Complex with An Engineered Binder, PDB code: 7l97:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of STAMBPL1 in Complex with An Engineered Binder


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of STAMBPL1 in Complex with An Engineered Binder within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:28.8 occ:1.00 NE2 A:HIS410 2.1 28.6 1.0 NE2 A:HIS362 2.1 26.0 1.0 NE2 A:HIS408 2.2 28.6 1.0 SG A:CYS402 2.3 30.1 1.0 CE1 A:HIS410 2.9 28.6 1.0 CE1 A:HIS362 3.1 27.2 1.0 CD2 A:HIS408 3.1 27.4 1.0 CD2 A:HIS410 3.1 28.3 1.0 CD2 A:HIS362 3.2 26.1 1.0 CB A:CYS402 3.2 34.2 1.0 CE1 A:HIS408 3.3 27.4 1.0 ND1 A:HIS410 4.0 27.8 1.0 CG A:HIS410 4.2 28.4 1.0 ND1 A:HIS362 4.2 27.3 1.0 CG A:HIS408 4.3 30.1 1.0 CG A:HIS362 4.3 25.9 1.0 ND1 A:HIS408 4.3 29.5 1.0 O A:LYS404 4.4 35.4 1.0 CB A:LYS404 4.5 37.6 1.0 CA A:CYS402 4.6 34.0 1.0 N A:LYS404 4.8 33.8 1.0 C A:CYS402 4.8 31.5 1.0 O A:CYS402 4.9 29.9 1.0 CG A:LYS404 5.0 41.7 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of STAMBPL1 in Complex with An Engineered Binder


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of STAMBPL1 in Complex with An Engineered Binder within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:51.8 occ:1.00 OD2 A:ASP360 2.2 27.4 1.0 NE2 A:HIS347 2.3 28.6 1.0 NE2 A:HIS349 2.3 30.4 1.0 OD1 A:ASP360 2.4 26.8 1.0 CG A:ASP360 2.6 26.3 1.0 CD2 A:HIS347 2.9 28.0 1.0 CD2 A:HIS349 3.1 29.6 1.0 CE1 A:HIS349 3.3 30.3 1.0 CE1 A:HIS347 3.4 29.1 1.0 OE2 A:GLU292 4.0 39.0 1.0 CB A:ASP360 4.1 26.2 1.0 CG A:HIS347 4.2 28.0 1.0 OG A:SER357 4.3 31.3 1.0 CG A:HIS349 4.3 29.3 1.0 ND1 A:HIS349 4.4 30.9 1.0 ND1 A:HIS347 4.4 29.8 1.0 OE1 A:GLU292 4.6 37.1 1.0 CD A:GLU292 4.7 34.3 1.0 CA A:ASP360 5.0 25.9 1.0 CB A:SER357 5.0 30.9 1.0

Y.Guo, A.Dong, F.Hou, Y.Li, W.Zhang, C.H.Arrowsmith, A.M.Edwards, Y.Tong, Structural Genomics Consortium (Sgc). Crystal Structure of STAMBPL1 in Complex with An Engineered Binder To Be Published.