Zinc in PDB 7jl1: Cryo-Em Structure of Rig-I:Dsrna in Complex with Riplet Pryspry Domain (Monomer)

All present enzymatic activity of Cryo-Em Structure of Rig-I:Dsrna in Complex with Riplet Pryspry Domain (Monomer):
2.3.2.27; 3.6.4.13;

The structure of Cryo-Em Structure of Rig-I:Dsrna in Complex with Riplet Pryspry Domain (Monomer) also contains other interesting chemical elements:

Fluorine	(F)	4 atoms
Magnesium	(Mg)	1 atom
Aluminium	(Al)	1 atom

The binding sites of Zinc atom in the Cryo-Em Structure of Rig-I:Dsrna in Complex with Riplet Pryspry Domain (Monomer) (pdb code 7jl1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Rig-I:Dsrna in Complex with Riplet Pryspry Domain (Monomer), PDB code: 7jl1:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Rig-I:Dsrna in Complex with Riplet Pryspry Domain (Monomer)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Rig-I:Dsrna in Complex with Riplet Pryspry Domain (Monomer) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2004 b:0.5 occ:1.00 SG A:CYS813 2.3 62.4 1.0 SG A:CYS869 2.3 76.6 1.0 SG A:CYS864 2.3 71.2 1.0 SG A:CYS810 2.3 61.5 1.0 CB A:CYS869 3.2 76.6 1.0 CB A:CYS864 3.3 71.2 1.0 CB A:CYS810 3.3 61.5 1.0 CB A:CYS813 3.5 62.4 1.0 N A:CYS813 4.0 62.4 1.0 CA A:CYS813 4.3 62.4 1.0 CA A:CYS869 4.6 76.6 1.0 NE1 A:TRP873 4.6 55.3 1.0 C A:CYS869 4.7 76.6 1.0 CA A:CYS864 4.7 71.2 1.0 O A:CYS869 4.8 76.6 1.0 CA A:CYS810 4.8 61.5 1.0 CZ2 A:TRP873 4.8 55.3 1.0 C A:CYS813 4.9 62.4 1.0 C A:LYS812 4.9 59.5 1.0

K.Kato, S.Ahmad, Z.Zhu, J.M.Young, X.Mu, S.Park, H.S.Malik, S.Hur. Structural Analysis of Rig-I-Like Receptors Reveals Ancient Rules of Engagement Between Diverse Rna Helicases and Trim Ubiquitin Ligases Mol.Cell 2020.
ISSN: ISSN 1097-2765