Zinc in PDB 7jl0: Cryo-Em Structure of MDA5-Dsrna in Complex with TRIM65 Pspry Domain (Monomer)

All present enzymatic activity of Cryo-Em Structure of MDA5-Dsrna in Complex with TRIM65 Pspry Domain (Monomer):
3.6.4.13;

The structure of Cryo-Em Structure of MDA5-Dsrna in Complex with TRIM65 Pspry Domain (Monomer) also contains other interesting chemical elements:

Fluorine	(F)	4 atoms
Magnesium	(Mg)	1 atom
Aluminium	(Al)	1 atom

The binding sites of Zinc atom in the Cryo-Em Structure of MDA5-Dsrna in Complex with TRIM65 Pspry Domain (Monomer) (pdb code 7jl0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of MDA5-Dsrna in Complex with TRIM65 Pspry Domain (Monomer), PDB code: 7jl0:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of MDA5-Dsrna in Complex with TRIM65 Pspry Domain (Monomer)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of MDA5-Dsrna in Complex with TRIM65 Pspry Domain (Monomer) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1101 b:0.8 occ:1.00 SG A:CYS910 2.3 79.5 1.0 SG A:CYS907 2.3 67.2 1.0 SG A:CYS964 2.3 96.5 1.0 SG A:CYS962 2.3 82.0 1.0 CB A:CYS964 3.2 96.5 1.0 CB A:CYS907 3.3 67.2 1.0 CB A:CYS962 3.4 82.0 1.0 CB A:CYS910 3.5 79.5 1.0 N A:CYS910 3.8 79.5 1.0 N A:CYS964 3.8 96.5 1.0 CA A:CYS964 4.1 96.5 1.0 CA A:CYS910 4.2 79.5 1.0 N A:LYS963 4.5 82.3 1.0 CA A:CYS962 4.7 82.0 1.0 CA A:CYS907 4.8 67.2 1.0 OE1 A:GLN966 4.8 65.1 1.0 NE1 A:TRP968 4.8 52.4 1.0 C A:CYS910 4.8 79.5 1.0 C A:ASN909 4.9 71.0 1.0 C A:LYS963 4.9 82.3 1.0

K.Kato, S.Ahmad, Z.Zhu, J.M.Young, X.Mu, S.Park, H.S.Malik, S.Hur. Structural Analysis of Rig-I-Like Receptors Reveals Ancient Rules of Engagement Between Diverse Rna Helicases and Trim Ubiquitin Ligases Mol.Cell 2020.
ISSN: ISSN 1097-2765