Zinc in PDB 7ebk: Mouse TRIM66 Phd-Bromo Dual Domain Complexed with the H3(1-24) K9ME3K18AC Peptide

The structure of Mouse TRIM66 Phd-Bromo Dual Domain Complexed with the H3(1-24) K9ME3K18AC Peptide, PDB code: 7ebk was solved by Z.Wang, J.Jiang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.83 / 1.74
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	64.646, 64.646, 251.744, 90, 90, 120
R / Rfree (%)	21.3 / 22.8

The binding sites of Zinc atom in the Mouse TRIM66 Phd-Bromo Dual Domain Complexed with the H3(1-24) K9ME3K18AC Peptide (pdb code 7ebk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Mouse TRIM66 Phd-Bromo Dual Domain Complexed with the H3(1-24) K9ME3K18AC Peptide, PDB code: 7ebk:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Mouse TRIM66 Phd-Bromo Dual Domain Complexed with the H3(1-24) K9ME3K18AC Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mouse TRIM66 Phd-Bromo Dual Domain Complexed with the H3(1-24) K9ME3K18AC Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1201 b:31.3 occ:1.00 ND1 A:HIS1019 2.1 28.4 1.0 SG A:CYS1002 2.3 34.6 1.0 SG A:CYS1022 2.3 32.0 1.0 SG A:CYS999 2.3 31.3 1.0 CB A:CYS999 3.0 32.7 1.0 CE1 A:HIS1019 3.1 36.8 1.0 CG A:HIS1019 3.2 30.5 1.0 CB A:CYS1022 3.2 23.9 1.0 CB A:CYS1002 3.3 34.0 1.0 CB A:HIS1019 3.5 28.9 1.0 N A:CYS1002 3.8 32.3 1.0 N A:HIS1019 4.1 30.1 1.0 CA A:CYS1002 4.1 31.5 1.0 NE2 A:HIS1019 4.2 33.3 1.0 CD2 A:HIS1019 4.3 31.6 1.0 CA A:HIS1019 4.4 28.8 1.0 CA A:CYS999 4.5 33.6 1.0 CA A:CYS1022 4.6 26.0 1.0 CB A:VAL1001 4.7 26.5 1.0 O A:HOH1470 4.8 37.5 1.0 C A:CYS1002 4.8 37.3 1.0 C A:VAL1001 4.9 31.0 1.0

Zinc binding site 2 out of 2 in the Mouse TRIM66 Phd-Bromo Dual Domain Complexed with the H3(1-24) K9ME3K18AC Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mouse TRIM66 Phd-Bromo Dual Domain Complexed with the H3(1-24) K9ME3K18AC Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1202 b:32.4 occ:1.00 SG A:CYS1014 2.2 33.4 1.0 SG A:CYS1011 2.3 31.1 1.0 SG A:CYS1040 2.3 32.7 1.0 SG A:CYS1037 2.4 26.3 1.0 CB A:CYS1040 3.3 25.2 1.0 CB A:CYS1011 3.3 31.6 1.0 CB A:CYS1014 3.3 37.7 1.0 CB A:CYS1037 3.5 27.2 1.0 N A:CYS1014 3.8 38.1 1.0 N A:CYS1037 3.9 27.0 1.0 CA A:CYS1014 4.1 40.9 1.0 N A:CYS1040 4.1 32.5 1.0 CA A:CYS1037 4.2 29.5 1.0 O A:HOH1432 4.2 40.9 1.0 CA A:CYS1040 4.3 32.7 1.0 C A:ARG1013 4.5 41.2 1.0 O A:HOH1455 4.6 43.8 1.0 O A:CYS1037 4.7 28.9 1.0 C A:CYS1037 4.7 28.7 1.0 CB A:ARG1013 4.7 34.9 1.0 CA A:CYS1011 4.7 29.3 1.0 C A:CYS1014 4.8 38.4 1.0 O A:CYS1014 4.8 40.3 1.0 N A:ARG1013 4.8 39.5 1.0 OH A:TYR1018 4.9 27.1 1.0 CA A:ARG1013 4.9 39.4 1.0

F.Zuo, J.Jiang, H.Fu, K.Yan, R.Liefke, J.Zhang, Y.Hong, Z.Chang, N.Liu, Z.Wang, Q.Xi. A TRIM66/DAX1/Dux Axis Suppresses the Totipotent 2-Cell-Like State in Murine Embryonic Stem Cells. Cell Stem Cell V. 29 948 2022.
ISSN: ISSN 1875-9777
PubMed: 35659877
DOI: 10.1016/J.STEM.2022.05.004