Zinc in PDB 6zxe: Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F2

All present enzymatic activity of Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F2:
2.7.11.1; 4.2.99.18;

The binding sites of Zinc atom in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F2 (pdb code 6zxe). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F2, PDB code: 6zxe:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F2 within 5.0Å range: probe atom residue distance (Å) B Occ y:Zn500 b:21.8 occ:1.00 SG y:CYS270 2.3 5.5 1.0 SG y:CYS285 2.4 5.8 1.0 SG y:CYS273 2.4 4.7 1.0 SG y:CYS288 2.4 5.0 1.0 CB y:CYS270 2.9 5.5 1.0 CB y:CYS285 3.0 5.8 1.0 CB y:CYS273 3.6 4.7 1.0 CB y:CYS288 3.7 5.0 1.0 N y:CYS273 4.0 4.7 1.0 N y:CYS288 4.1 5.0 1.0 OG1 y:THR292 4.3 4.3 1.0 CA y:CYS273 4.3 4.7 1.0 CA y:CYS270 4.4 5.5 1.0 CA y:CYS288 4.5 5.0 1.0 CA y:CYS285 4.5 5.8 1.0 C y:CYS273 4.8 4.7 1.0 O y:LYS275 4.9 5.6 1.0 CB y:HIS287 4.9 5.3 1.0 N y:PHE274 4.9 4.4 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F2 within 5.0Å range: probe atom residue distance (Å) B Occ f:Zn500 b:36.9 occ:1.00 NZ f:LYS143 2.4 27.7 1.0 OP1 2:C1311 3.5 44.7 1.0 CE f:LYS143 3.8 27.7 1.0 CD f:LYS143 4.5 27.7 1.0 NZ M:LYS44 4.6 24.2 1.0 CG2 f:VAL130 4.8 26.5 1.0 CE M:LYS44 4.9 24.2 1.0 P 2:C1311 5.0 44.7 1.0

M.Ameismeier, I.Zemp, J.Van Den Heuvel, M.Thoms, O.Berninghausen, U.Kutay, R.Beckmann. Structural Basis For the Final Steps of Human 40S Ribosome Maturation. Nature V. 587 683 2020.
ISSN: ESSN 1476-4687
PubMed: 33208940
DOI: 10.1038/S41586-020-2929-X