Zinc in PDB 6x4y: Mfd-Bound E.Coli Rna Polymerase Elongation Complex - IV State

All present enzymatic activity of Mfd-Bound E.Coli Rna Polymerase Elongation Complex - IV State:
2.7.7.6;

The structure of Mfd-Bound E.Coli Rna Polymerase Elongation Complex - IV State also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Zinc atom in the Mfd-Bound E.Coli Rna Polymerase Elongation Complex - IV State (pdb code 6x4y). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Mfd-Bound E.Coli Rna Polymerase Elongation Complex - IV State, PDB code: 6x4y:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Mfd-Bound E.Coli Rna Polymerase Elongation Complex - IV State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mfd-Bound E.Coli Rna Polymerase Elongation Complex - IV State within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn1502 b:181.6 occ:1.00 SG J:CYS70 2.3 112.9 1.0 SG J:CYS72 2.3 118.5 1.0 SG J:CYS88 2.3 111.1 1.0 SG J:CYS85 2.3 112.3 1.0 CB J:CYS85 3.2 112.3 1.0 CB J:CYS72 3.4 118.5 1.0 N J:CYS72 3.6 118.5 1.0 N J:CYS88 3.6 111.1 1.0 CB J:CYS88 3.7 111.1 1.0 CB J:CYS70 4.0 112.9 1.0 CA J:CYS72 4.1 118.5 1.0 CA J:CYS88 4.2 111.1 1.0 CB J:LYS87 4.2 118.2 1.0 N J:LEU71 4.4 108.1 1.0 N J:LYS87 4.4 118.2 1.0 CG2 J:VAL90 4.4 99.8 1.0 C J:LYS87 4.5 118.2 1.0 CB J:LYS74 4.6 113.5 1.0 CA J:LYS87 4.6 118.2 1.0 CA J:CYS85 4.7 112.3 1.0 N J:GLY73 4.7 114.4 1.0 N J:GLY89 4.7 104.1 1.0 C J:CYS72 4.7 118.5 1.0 C J:LEU71 4.8 108.1 1.0 C J:CYS88 4.8 111.1 1.0 CD J:LYS87 4.9 118.2 1.0 N J:GLU86 5.0 113.9 1.0 CA J:CYS70 5.0 112.9 1.0

Zinc binding site 2 out of 2 in the Mfd-Bound E.Coli Rna Polymerase Elongation Complex - IV State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mfd-Bound E.Coli Rna Polymerase Elongation Complex - IV State within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn1503 b:103.8 occ:1.00 CB J:CYS895 2.1 70.2 1.0 SG J:CYS898 2.3 66.0 1.0 SG J:CYS814 2.3 80.1 1.0 SG J:CYS888 2.3 70.2 1.0 SG J:CYS895 2.3 70.2 1.0 CB J:CYS814 2.7 80.1 1.0 CB J:CYS898 3.1 66.0 1.0 NH2 J:ARG883 3.5 69.5 1.0 CB J:CYS888 3.5 70.2 1.0 CA J:CYS895 3.6 70.2 1.0 N J:CYS814 3.7 80.1 1.0 CA J:CYS814 3.8 80.1 1.0 N J:CYS895 4.1 70.2 1.0 N J:CYS898 4.2 66.0 1.0 CA J:CYS888 4.2 70.2 1.0 CA J:CYS898 4.3 66.0 1.0 C J:CYS895 4.5 70.2 1.0 N J:ASP889 4.6 77.9 1.0 CZ J:ARG883 4.7 69.5 1.0 C J:CYS814 4.7 80.1 1.0 OG1 J:THR890 4.7 72.2 1.0 OG1 J:THR816 4.8 81.6 1.0 C J:CYS888 4.8 70.2 1.0 N J:GLY815 4.9 81.6 1.0 C J:ASP813 4.9 75.5 1.0 N J:ALA896 5.0 61.8 1.0

J.Y.Kang, E.Llewellyn, J.Chen, P.D.B.Olinares, J.Brewer, B.T.Chait, E.A.Campbell, S.A.Darst. Structural Basis For Transcription Complex Disruption By the Mfd Translocase. Elife V. 10 2021.
ISSN: ESSN 2050-084X
PubMed: 33480355
DOI: 10.7554/ELIFE.62117