Zinc in PDB 6rfs: Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4

All present enzymatic activity of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4:
1.6.5.3; 1.6.99.3; 7.1.1.2;

The structure of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 also contains other interesting chemical elements:

Iron

(Fe)

28 atoms

The binding sites of Zinc atom in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 (pdb code 6rfs). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4, PDB code: 6rfs:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range: probe atom residue distance (Å) B Occ M:Zn201 b:0.5 occ:1.00 NE2 M:HIS110 2.0 0.8 1.0 CE1 M:HIS110 2.1 0.8 1.0 SG M:CYS97 2.3 0.1 1.0 SG M:CYS125 2.3 1.0 1.0 SG M:CYS128 2.3 0.2 1.0 CB M:CYS128 2.9 0.2 1.0 CD2 M:HIS110 2.9 0.8 1.0 N M:CYS128 3.0 0.2 1.0 ND1 M:HIS110 3.0 0.8 1.0 CB M:CYS125 3.1 1.0 1.0 CB M:CYS97 3.4 0.1 1.0 CG M:HIS110 3.4 0.8 1.0 CA M:CYS128 3.5 0.2 1.0 CB M:TYR127 3.9 0.4 1.0 C M:TYR127 4.0 0.4 1.0 O M:CYS125 4.1 1.0 1.0 N M:TYR127 4.2 0.4 1.0 C M:CYS125 4.2 1.0 1.0 CA M:TYR127 4.3 0.4 1.0 CA M:CYS125 4.3 1.0 1.0 C M:CYS128 4.5 0.2 1.0 C M:CYS97 4.6 0.1 1.0 N M:GLY129 4.6 0.9 1.0 CA M:CYS97 4.6 0.1 1.0 CB M:HIS110 4.8 0.8 1.0 OG1 M:THR130 4.8 0.3 1.0 CD2 M:TYR127 4.8 0.4 1.0 O M:CYS97 4.8 0.1 1.0 CG M:TYR127 4.9 0.4 1.0 N M:ASP98 4.9 0.3 1.0 N M:GLN126 4.9 0.2 1.0

K.Parey, O.Haapanen, V.Sharma, H.Kofeler, T.Zullig, S.Prinz, K.Siegmund, I.Wittig, D.J.Mills, J.Vonck, W.Kuhlbrandt, V.Zickermann. High-Resolution Cryo-Em Structures of Respiratory Complex I: Mechanism, Assembly, and Disease. Sci Adv V. 5 X9484 2019.
ISSN: ESSN 2375-2548
PubMed: 31844670
DOI: 10.1126/SCIADV.AAX9484