Zinc in PDB 6p59: Crystal Structure of Sivrcm Vif-Cbfbeta-Elob-Eloc Complex

The structure of Crystal Structure of Sivrcm Vif-Cbfbeta-Elob-Eloc Complex, PDB code: 6p59 was solved by J.M.Binning, N.M.Chesarino, M.Emerman, J.D.Gross, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.12 / 2.94
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	110.220, 112.489, 125.697, 90.00, 90.00, 90.00
R / Rfree (%)	23.5 / 26.8

The binding sites of Zinc atom in the Crystal Structure of Sivrcm Vif-Cbfbeta-Elob-Eloc Complex (pdb code 6p59). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Sivrcm Vif-Cbfbeta-Elob-Eloc Complex, PDB code: 6p59:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Sivrcm Vif-Cbfbeta-Elob-Eloc Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Sivrcm Vif-Cbfbeta-Elob-Eloc Complex within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn301 b:79.6 occ:1.00 NE2 F:HIS145 1.6 0.1 1.0 CE1 F:HIS145 2.1 0.7 1.0 NE2 F:HIS115 2.2 81.1 1.0 SG F:CYS139 2.3 92.1 1.0 SG F:CYS121 2.5 0.8 1.0 CD2 F:HIS145 2.9 0.0 1.0 CD2 F:HIS115 2.9 78.2 1.0 CE1 F:HIS115 3.3 82.3 1.0 CB F:CYS139 3.4 98.7 1.0 ND1 F:HIS145 3.4 0.9 1.0 CB F:CYS121 3.6 0.6 1.0 CG F:HIS145 3.8 0.5 1.0 CA F:CYS121 4.0 0.2 1.0 CG F:HIS115 4.2 79.5 1.0 ND1 F:HIS115 4.3 81.9 1.0 O F:PHE141 4.3 91.9 1.0 CA F:CYS139 4.5 0.4 1.0 O F:PRO120 4.6 0.9 1.0 CE1 F:TYR154 4.8 90.9 1.0 N F:PHE122 4.9 0.4 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Sivrcm Vif-Cbfbeta-Elob-Eloc Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Sivrcm Vif-Cbfbeta-Elob-Eloc Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:58.6 occ:1.00 NE2 B:HIS145 1.9 85.6 1.0 NE2 B:HIS115 2.0 79.8 1.0 SG B:CYS139 2.2 92.8 1.0 SG B:CYS121 2.3 48.3 1.0 CD2 B:HIS145 2.8 81.8 1.0 CD2 B:HIS115 2.9 71.8 1.0 CE1 B:HIS115 3.0 73.0 1.0 CE1 B:HIS145 3.0 82.5 1.0 CB B:CYS121 3.3 49.9 1.0 CB B:CYS139 3.5 88.4 1.0 CA B:CYS121 3.7 54.5 1.0 CG B:HIS145 4.0 75.6 1.0 ND1 B:HIS115 4.0 65.3 1.0 ND1 B:HIS145 4.0 78.3 1.0 CG B:HIS115 4.0 62.0 1.0 O B:PHE141 4.1 76.9 1.0 O B:PRO120 4.3 60.4 1.0 CA B:CYS139 4.4 85.1 1.0 N B:CYS121 4.6 58.3 1.0 C B:PHE141 4.8 75.6 1.0 C B:PRO120 4.8 61.5 1.0 CE1 B:TYR154 4.8 64.1 1.0 N B:PHE122 4.9 60.3 1.0 C B:CYS121 4.9 58.2 1.0

J.M.Binning, N.M.Chesarino, M.Emerman, J.D.Gross. Structural Basis For A Species-Specific Determinant of An Siv Vif Protein Toward Hominid APOBEC3G Antagonism. Cell Host Microbe V. 26 739 2019.
ISSN: ESSN 1934-6069
PubMed: 31830442
DOI: 10.1016/J.CHOM.2019.10.014