Zinc in PDB 6iiw: Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15

All present enzymatic activity of Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15:
2.3.2.27;

The structure of Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15, PDB code: 6iiw was solved by K.Arita, S.Kori, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.69 / 1.70
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	36.716, 36.716, 220.147, 90.00, 90.00, 120.00
R / Rfree (%)	17.6 / 18.9

The binding sites of Zinc atom in the Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15 (pdb code 6iiw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15, PDB code: 6iiw:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:21.6 occ:1.00 SG A:CYS302 2.3 25.0 1.0 SG A:CYS313 2.3 18.7 1.0 SG A:CYS316 2.3 22.0 1.0 SG A:CYS305 2.4 21.8 1.0 CB A:CYS302 3.0 30.1 1.0 CB A:CYS313 3.2 17.4 1.0 CB A:CYS305 3.3 24.6 1.0 CB A:CYS316 3.4 22.0 1.0 N A:CYS305 3.7 24.6 1.0 N A:CYS316 3.8 15.1 1.0 CA A:CYS305 4.1 23.6 1.0 CA A:CYS316 4.2 15.0 1.0 O A:HOH503 4.3 37.5 1.0 NH2 A:ARG324 4.4 20.4 1.0 CA A:CYS302 4.5 28.5 1.0 CB A:HIS304 4.6 28.2 1.0 CB A:VAL315 4.6 20.6 1.0 CA A:CYS313 4.6 16.7 1.0 C A:HIS304 4.6 26.2 1.0 C A:VAL315 4.7 19.7 1.0 N A:HIS304 4.9 28.2 1.0 C A:CYS302 4.9 28.8 1.0 O A:HOH570 4.9 30.1 1.0 O A:CYS302 4.9 29.1 1.0 C A:CYS305 4.9 28.1 1.0 CA A:HIS304 4.9 27.6 1.0 NH1 A:ARG324 4.9 21.3 1.0 C A:CYS316 4.9 19.5 1.0 N A:VAL315 5.0 19.6 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:18.6 occ:1.00 ND1 A:HIS341 2.1 20.7 1.0 SG A:CYS344 2.3 22.8 1.0 SG A:CYS318 2.3 15.4 1.0 SG A:CYS321 2.3 19.5 1.0 CB A:CYS318 3.0 14.7 1.0 CG A:HIS341 3.0 15.4 1.0 CE1 A:HIS341 3.1 17.6 1.0 CB A:CYS321 3.3 18.9 1.0 CB A:HIS341 3.3 16.1 1.0 CB A:CYS344 3.4 19.8 1.0 N A:CYS321 3.8 19.6 1.0 CA A:CYS321 4.1 17.9 1.0 N A:HIS341 4.2 16.7 1.0 NE2 A:HIS341 4.2 21.4 1.0 CD2 A:HIS341 4.2 19.8 1.0 CA A:HIS341 4.4 16.9 1.0 CA A:CYS318 4.5 14.1 1.0 CA A:CYS344 4.7 20.4 1.0 O A:HOH573 4.7 38.7 1.0 CB A:LEU320 4.8 20.4 1.0 C A:CYS321 4.8 17.6 1.0 CE1 A:TYR343 4.8 27.3 1.0 C A:LEU320 4.8 22.4 1.0 N A:GLY322 4.8 16.6 1.0 N A:GLY323 4.9 15.3 1.0 N A:CYS344 5.0 20.6 1.0 C A:CYS318 5.0 13.9 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn403 b:19.6 occ:1.00 SG A:CYS363 2.2 20.8 1.0 SG A:CYS360 2.3 20.5 1.0 SG A:CYS336 2.3 19.1 1.0 SG A:CYS333 2.4 19.3 1.0 CB A:CYS333 3.2 18.3 1.0 CB A:CYS363 3.2 27.9 1.0 CB A:CYS336 3.3 18.3 1.0 CB A:CYS360 3.4 20.4 1.0 N A:CYS336 3.7 19.9 1.0 N A:CYS360 4.0 20.2 1.0 CA A:CYS336 4.1 19.8 1.0 N A:CYS363 4.1 23.2 1.0 CA A:CYS360 4.2 18.4 1.0 CA A:CYS363 4.3 24.2 1.0 O A:HOH547 4.5 24.4 1.0 CB A:GLU335 4.5 25.5 1.0 CA A:CYS333 4.6 17.6 1.0 C A:GLU362 4.7 27.4 1.0 C A:CYS360 4.7 23.4 1.0 O A:CYS360 4.8 20.1 1.0 CB A:GLU362 4.8 21.0 1.0 C A:GLU335 4.8 24.4 1.0 C A:CYS336 4.8 18.0 1.0 CE1 A:PHE340 4.9 19.1 1.0 N A:ASP337 4.9 18.1 1.0 N A:GLU362 5.0 19.2 1.0 N A:GLU335 5.0 20.5 1.0

Zinc binding site 4 out of 4 in the Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn404 b:17.9 occ:0.52 CE1 A:HIS319 2.1 17.9 1.0 OE1 A:GLU362 2.3 30.6 1.0 OE2 A:GLU362 2.4 29.6 1.0 CD A:GLU362 2.6 29.4 1.0 ND1 A:HIS319 3.0 24.3 1.0 NE2 A:HIS319 3.1 21.9 1.0 O A:HOH547 4.1 24.4 1.0 CG A:GLU362 4.1 24.5 1.0 O A:HOH536 4.2 24.9 1.0 CG A:HIS319 4.2 14.4 1.0 CD2 A:HIS319 4.2 14.4 1.0 CB A:GLU362 5.0 21.0 1.0

K.Arita, S.Kori. Crystal Structure of Human UHRF1 Phd Finger in Complex with PAF15 (Would Be Changed After the Data Is Released) To Be Published.