Zinc in PDB 5v3c: Crystal Structure of Tgt in Complex with 4-(Aminomethane)Cyclohexane- 1-Carboxylic Acid

All present enzymatic activity of Crystal Structure of Tgt in Complex with 4-(Aminomethane)Cyclohexane- 1-Carboxylic Acid:
2.4.2.29;

The structure of Crystal Structure of Tgt in Complex with 4-(Aminomethane)Cyclohexane- 1-Carboxylic Acid, PDB code: 5v3c was solved by E.Hassaan, A.Heine, G.Klebe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.33 / 1.42
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	88.746, 63.739, 70.430, 90.00, 92.59, 90.00
R / Rfree (%)	13.4 / 15.5

The binding sites of Zinc atom in the Crystal Structure of Tgt in Complex with 4-(Aminomethane)Cyclohexane- 1-Carboxylic Acid (pdb code 5v3c). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Tgt in Complex with 4-(Aminomethane)Cyclohexane- 1-Carboxylic Acid, PDB code: 5v3c:

Zinc binding site 1 out of 1 in the Crystal Structure of Tgt in Complex with 4-(Aminomethane)Cyclohexane- 1-Carboxylic Acid


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Tgt in Complex with 4-(Aminomethane)Cyclohexane- 1-Carboxylic Acid within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:13.8 occ:1.00 ND1 A:HIS349 2.1 12.4 1.0 SG A:CYS320 2.3 13.3 1.0 SG A:CYS318 2.3 15.6 1.0 SG A:CYS323 2.3 14.0 1.0 CE1 A:HIS349 3.0 14.1 1.0 HB2 A:CYS323 3.0 17.1 1.0 HE1 A:HIS349 3.0 16.9 1.0 HB3 A:CYS318 3.1 20.1 1.0 HB3 A:CYS320 3.2 16.4 1.0 CG A:HIS349 3.3 11.7 1.0 CB A:CYS323 3.3 14.3 1.0 CB A:CYS318 3.3 16.7 1.0 HB2 A:HIS349 3.3 14.3 1.0 H A:CYS323 3.3 16.3 1.0 CB A:CYS320 3.3 13.7 1.0 H A:CYS320 3.5 19.1 1.0 HA A:HIS349 3.5 13.0 1.0 HB2 A:CYS318 3.6 20.1 1.0 CB A:HIS349 3.7 11.9 1.0 HB A:VAL322 3.9 16.6 1.0 N A:CYS323 3.9 13.6 1.0 HB3 A:CYS323 4.0 17.1 1.0 HB2 A:CYS320 4.1 16.4 1.0 CA A:HIS349 4.1 10.9 1.0 N A:CYS320 4.1 15.9 1.0 NE2 A:HIS349 4.2 13.6 1.0 HB2 A:LEU314 4.2 15.7 1.0 CA A:CYS320 4.2 14.9 1.0 CA A:CYS323 4.2 14.1 1.0 CD2 A:HIS349 4.3 11.8 1.0 HE22 A:GLN356 4.4 25.0 1.0 HB3 A:ALA352 4.5 15.7 1.0 HD12 A:LEU314 4.5 15.2 1.0 H A:ASP315 4.5 17.0 1.0 O A:HIS349 4.5 11.2 1.0 HB3 A:ASP315 4.6 21.1 1.0 HA A:CYS323 4.6 16.9 1.0 HB3 A:HIS349 4.6 14.3 1.0 CA A:CYS318 4.6 18.1 1.0 O A:CYS320 4.7 15.5 1.0 C A:CYS320 4.7 14.4 1.0 H A:VAL322 4.7 16.3 1.0 C A:CYS318 4.8 19.1 1.0 C A:HIS349 4.8 10.8 1.0 CB A:VAL322 4.8 13.9 1.0 HE2 A:HIS349 4.9 16.3 1.0 C A:VAL322 4.9 13.8 1.0 O A:CYS318 5.0 20.3 1.0

E.Hassaan, A.Heine, G.Klebe. Crystal Structure of Tgt in Complex with 4-(Aminomethane)Cyclohexane-1-Carboxylic Acid To Be Published.