Zinc in PDB 4z0r: Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide

The structure of Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide, PDB code: 4z0r was solved by Y.Liu, W.Tempel, C.Bountra, C.H.Arrowsmith, A.M.Edwards, J.Min, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.44 / 1.75
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	126.659, 126.659, 63.271, 90.00, 90.00, 120.00
R / Rfree (%)	17.7 / 19.2

The binding sites of Zinc atom in the Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide (pdb code 4z0r). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide, PDB code: 4z0r:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:31.3 occ:1.00 SG A:CYS60 2.3 30.0 1.0 SG A:CYS38 2.3 31.1 1.0 SG A:CYS33 2.4 29.7 1.0 SG A:CYS71 2.4 34.8 1.0 CB A:CYS33 3.1 28.4 1.0 CB A:CYS38 3.1 32.0 1.0 CB A:CYS71 3.2 33.6 1.0 CB A:CYS60 3.3 30.4 1.0 CA A:CYS71 3.4 31.6 1.0 N A:CYS60 3.9 30.2 1.0 N A:CYS71 4.1 31.6 1.0 CA A:CYS60 4.2 30.0 1.0 CB A:ASN35 4.5 36.5 1.0 CA A:CYS38 4.6 32.5 1.0 CA A:CYS33 4.6 27.7 1.0 C A:CYS71 4.7 32.8 1.0 N A:LEU39 4.8 31.7 1.0 N A:LYS40 4.9 28.9 1.0 O A:CYS71 4.9 31.9 1.0 C A:ASN70 4.9 31.1 1.0 ND2 A:ASN35 5.0 39.3 1.0 C A:CYS38 5.0 30.8 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:26.1 occ:1.00 SG B:CYS71 2.3 25.3 1.0 SG B:CYS60 2.3 26.9 1.0 SG B:CYS38 2.3 26.3 1.0 SG B:CYS33 2.3 26.2 1.0 CB B:CYS33 3.1 28.2 1.0 CB B:CYS38 3.1 26.9 1.0 CB B:CYS71 3.3 23.6 1.0 CB B:CYS60 3.3 24.2 1.0 CA B:CYS71 3.5 23.5 1.0 N B:CYS60 3.9 25.0 1.0 N B:CYS71 4.1 23.5 1.0 CA B:CYS60 4.2 24.6 1.0 O C:HOH1130 4.4 25.1 1.0 CB B:ASN35 4.4 28.0 1.0 CA B:CYS33 4.5 28.7 1.0 CA B:CYS38 4.6 28.9 1.0 C B:CYS71 4.7 24.9 1.0 ND2 B:ASN35 4.8 28.2 1.0 O B:CYS71 4.9 23.7 1.0 C B:ASN70 4.9 23.8 1.0 N B:LEU39 4.9 31.3 1.0 NH2 B:ARG42 4.9 25.5 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1001 b:22.5 occ:1.00 SG C:CYS71 2.3 23.7 1.0 SG C:CYS33 2.3 23.7 1.0 SG C:CYS38 2.3 24.6 1.0 SG C:CYS60 2.4 21.8 1.0 CB C:CYS38 3.1 24.9 1.0 CB C:CYS33 3.1 23.3 1.0 CB C:CYS71 3.2 23.6 1.0 CB C:CYS60 3.3 20.8 1.0 CA C:CYS71 3.5 23.0 1.0 N C:CYS60 3.9 21.2 1.0 N C:CYS71 4.1 21.9 1.0 CA C:CYS60 4.2 21.3 1.0 CB C:ASN35 4.4 26.4 1.0 CA C:CYS38 4.5 25.2 1.0 CA C:CYS33 4.6 21.8 1.0 C C:CYS71 4.8 24.0 1.0 N C:LEU39 4.8 25.2 1.0 ND2 C:ASN35 4.8 25.6 1.0 N C:LYS40 4.9 22.7 1.0 C C:ASN70 4.9 21.7 1.0 O C:CYS71 4.9 23.5 1.0 CB C:LYS40 4.9 21.4 1.0 C C:CYS38 5.0 24.0 1.0

Y.Liu, W.Tempel, C.Bountra, C.H.Arrowsmith, A.M.Edwards, J.Min. Crystal Structure of the Cw Domain of ZCWPW2 Mutant F78R in Complex with Histone H3 Peptide To Be Published.