Zinc in PDB 2wfq: Crystal Structure of the N-Terminal Signalling Domain of Human Dhh Without Calcium

The structure of Crystal Structure of the N-Terminal Signalling Domain of Human Dhh Without Calcium, PDB code: 2wfq was solved by B.Bishop, A.R.Aricescu, K.Harlos, C.A.O'callaghan, E.Y.Jones, C.Siebold, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.85
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	40.563, 42.048, 84.301, 90.00, 90.00, 90.00
R / Rfree (%)	18.724 / 22.895

The binding sites of Zinc atom in the Crystal Structure of the N-Terminal Signalling Domain of Human Dhh Without Calcium (pdb code 2wfq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the N-Terminal Signalling Domain of Human Dhh Without Calcium, PDB code: 2wfq:

Zinc binding site 1 out of 1 in the Crystal Structure of the N-Terminal Signalling Domain of Human Dhh Without Calcium


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the N-Terminal Signalling Domain of Human Dhh Without Calcium within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1204 b:30.0 occ:1.00 OD1 A:ASP148 1.9 15.7 1.0 NE2 A:HIS141 2.1 12.7 1.0 ND1 A:HIS183 2.2 12.5 1.0 CG A:ASP148 2.7 14.1 1.0 OD2 A:ASP148 2.8 14.3 1.0 CE1 A:HIS141 3.0 14.2 1.0 CE1 A:HIS183 3.1 16.3 1.0 CD2 A:HIS141 3.2 13.7 1.0 CG A:HIS183 3.2 13.4 1.0 CB A:HIS183 3.5 12.5 1.0 CB A:ASP148 4.1 15.2 1.0 ND1 A:HIS141 4.2 11.4 1.0 CA A:HIS183 4.2 13.2 1.0 NE2 A:HIS183 4.2 13.1 1.0 CG A:HIS141 4.3 11.9 1.0 CD2 A:HIS183 4.3 12.0 1.0 O A:LEU147 4.3 14.9 1.0 N A:ASP148 4.4 15.0 1.0 CE1 A:HIS135 4.5 29.7 1.0 C A:LEU147 4.5 14.3 1.0 CA A:ASP148 4.5 14.8 1.0 NE2 A:HIS181 4.7 20.7 1.0 ND1 A:HIS135 4.8 30.7 1.0 CD2 A:HIS181 4.9 21.0 1.0

B.Bishop, A.R.Aricescu, K.Harlos, C.A.O'callaghan, E.Y.Jones, C.Siebold. Structural Insights Into Hedgehog Ligand Sequestration By the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol. V. 16 698 2009.
ISSN: ISSN 1545-9993
PubMed: 19561611
DOI: 10.1038/NSMB.1607