Zinc in PDB 2lgl: uc(Nmr) Structure of the UHRF1 Phd Domain

The binding sites of Zinc atom in the uc(Nmr) Structure of the UHRF1 Phd Domain (pdb code 2lgl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the uc(Nmr) Structure of the UHRF1 Phd Domain, PDB code: 2lgl:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the uc(Nmr) Structure of the UHRF1 Phd Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of uc(Nmr) Structure of the UHRF1 Phd Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn380 b:0.0 occ:1.00 SG A:CYS318 2.3 0.0 1.0 SG A:CYS315 2.3 0.0 1.0 SG A:CYS326 2.3 0.0 1.0 SG A:CYS329 2.3 0.0 1.0 HA A:CYS315 2.8 0.0 1.0 HA A:CYS326 2.9 0.0 1.0 HB2 A:CYS329 3.2 0.0 1.0 CB A:CYS315 3.3 0.0 1.0 CB A:CYS318 3.3 0.0 1.0 HB2 A:CYS318 3.3 0.0 1.0 HB3 A:CYS315 3.4 0.0 1.0 CB A:CYS326 3.4 0.0 1.0 CB A:CYS329 3.4 0.0 1.0 HB3 A:CYS318 3.5 0.0 1.0 CA A:CYS315 3.5 0.0 1.0 HB3 A:CYS326 3.6 0.0 1.0 CA A:CYS326 3.6 0.0 1.0 H A:CYS329 3.7 0.0 1.0 H A:LYS316 3.9 0.0 1.0 HB3 A:CYS329 4.0 0.0 1.0 HB2 A:CYS315 4.3 0.0 1.0 HB2 A:CYS326 4.4 0.0 1.0 H A:CYS318 4.4 0.0 1.0 O A:LEU325 4.4 0.0 1.0 N A:CYS329 4.4 0.0 1.0 N A:LYS316 4.5 0.0 1.0 C A:CYS315 4.5 0.0 1.0 CA A:CYS329 4.6 0.0 1.0 O A:SER314 4.6 0.0 1.0 N A:CYS326 4.6 0.0 1.0 N A:CYS315 4.6 0.0 1.0 HB A:VAL328 4.7 0.0 1.0 CA A:CYS318 4.7 0.0 1.0 C A:CYS326 4.7 0.0 1.0 H A:ALA330 4.8 0.0 1.0 N A:CYS318 4.9 0.0 1.0 C A:LEU325 4.9 0.0 1.0 C A:SER314 5.0 0.0 1.0

Zinc binding site 2 out of 3 in the uc(Nmr) Structure of the UHRF1 Phd Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of uc(Nmr) Structure of the UHRF1 Phd Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn381 b:0.0 occ:1.00 NE2 A:HIS354 2.0 0.0 1.0 SG A:CYS334 2.3 0.0 1.0 SG A:CYS357 2.3 0.0 1.0 SG A:CYS331 2.3 0.0 1.0 CD2 A:HIS354 2.7 0.0 1.0 HG3 A:GLN338 2.8 0.0 1.0 HD2 A:HIS354 2.9 0.0 1.0 CE1 A:HIS354 3.0 0.0 1.0 HB2 A:CYS334 3.1 0.0 1.0 HB3 A:CYS357 3.2 0.0 1.0 CB A:CYS357 3.2 0.0 1.0 HB2 A:CYS331 3.2 0.0 1.0 CB A:CYS334 3.3 0.0 1.0 CB A:CYS331 3.4 0.0 1.0 HB2 A:CYS357 3.4 0.0 1.0 HE1 A:HIS354 3.4 0.0 1.0 H A:CYS334 3.5 0.0 1.0 HB2 A:LEU333 3.6 0.0 1.0 HB3 A:CYS331 3.8 0.0 1.0 CG A:GLN338 3.8 0.0 1.0 HE22 A:GLN343 3.8 0.0 1.0 CG A:HIS354 3.8 0.0 1.0 HE21 A:GLN343 3.9 0.0 1.0 N A:CYS334 3.9 0.0 1.0 ND1 A:HIS354 3.9 0.0 1.0 HB3 A:CYS334 4.1 0.0 1.0 HG2 A:GLN338 4.1 0.0 1.0 NE2 A:GLN343 4.2 0.0 1.0 CA A:CYS334 4.3 0.0 1.0 CD A:GLN338 4.4 0.0 1.0 CB A:LEU333 4.5 0.0 1.0 HA A:HIS354 4.5 0.0 1.0 HB3 A:LEU333 4.6 0.0 1.0 CA A:CYS357 4.6 0.0 1.0 H A:CYS331 4.6 0.0 1.0 CA A:CYS331 4.7 0.0 1.0 HA A:CYS357 4.8 0.0 1.0 HA A:CYS334 4.8 0.0 1.0 C A:LEU333 4.8 0.0 1.0 O A:CYS331 4.8 0.0 1.0 HD1 A:HIS354 4.8 0.0 1.0 CB A:GLN338 4.8 0.0 1.0 HB2 A:GLN338 4.8 0.0 1.0 HE21 A:GLN338 4.8 0.0 1.0 NE2 A:GLN338 4.9 0.0 1.0 OE1 A:GLN338 4.9 0.0 1.0 H A:LEU333 4.9 0.0 1.0 HB3 A:GLN338 5.0 0.0 1.0

Zinc binding site 3 out of 3 in the uc(Nmr) Structure of the UHRF1 Phd Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of uc(Nmr) Structure of the UHRF1 Phd Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn382 b:0.0 occ:1.00 SG A:CYS376 2.3 0.0 1.0 SG A:CYS349 2.3 0.0 1.0 SG A:CYS373 2.3 0.0 1.0 SG A:CYS346 2.3 0.0 1.0 H A:CYS373 2.5 0.0 1.0 HB3 A:CYS376 3.1 0.0 1.0 HB2 A:CYS349 3.2 0.0 1.0 H A:CYS349 3.2 0.0 1.0 HB3 A:GLU348 3.2 0.0 1.0 N A:CYS373 3.3 0.0 1.0 CB A:CYS376 3.3 0.0 1.0 CB A:CYS349 3.4 0.0 1.0 H A:CYS376 3.4 0.0 1.0 CB A:CYS346 3.4 0.0 1.0 CB A:CYS373 3.5 0.0 1.0 HB3 A:CYS346 3.6 0.0 1.0 HB2 A:CYS346 3.6 0.0 1.0 HB3 A:CYS373 3.6 0.0 1.0 O A:CYS373 3.7 0.0 1.0 N A:CYS349 3.8 0.0 1.0 CA A:CYS373 3.9 0.0 1.0 HB3 A:TYR372 4.0 0.0 1.0 HA A:TYR372 4.0 0.0 1.0 N A:CYS376 4.0 0.0 1.0 HB3 A:GLU375 4.0 0.0 1.0 HD1 A:TYR372 4.1 0.0 1.0 HB2 A:CYS376 4.1 0.0 1.0 HB3 A:CYS349 4.2 0.0 1.0 C A:CYS373 4.2 0.0 1.0 CA A:CYS349 4.2 0.0 1.0 CB A:GLU348 4.3 0.0 1.0 C A:TYR372 4.3 0.0 1.0 CA A:CYS376 4.3 0.0 1.0 HB2 A:CYS373 4.4 0.0 1.0 OE1 A:GLU348 4.4 0.0 1.0 CA A:TYR372 4.5 0.0 1.0 H A:GLU348 4.6 0.0 1.0 C A:GLU348 4.6 0.0 1.0 HG2 A:GLU348 4.7 0.0 1.0 H A:GLU375 4.7 0.0 1.0 CB A:TYR372 4.8 0.0 1.0 CA A:CYS346 4.8 0.0 1.0 HA A:CYS349 4.9 0.0 1.0 HA A:CYS373 4.9 0.0 1.0 H A:ARG377 4.9 0.0 1.0 CD A:GLU348 4.9 0.0 1.0 CG A:GLU348 4.9 0.0 1.0 HB2 A:GLU348 4.9 0.0 1.0 CA A:GLU348 4.9 0.0 1.0

C.Wang, J.Shen, Z.Yang, P.Chen, B.Zhao, W.Hu, W.Lan, X.Tong, H.Wu, G.Li, C.Cao. Structural Basis For Site-Specific Reading of Unmodified R2 of Histone H3 Tail By UHRF1 Phd Finger. Cell Res. V. 21 1379 2011.
ISSN: ISSN 1001-0602
PubMed: 21808299
DOI: 10.1038/CR.2011.123