Zinc in PDB 2a25: Crystal Structure of SIAH1 Sbd Bound to the Peptide Ekpaavvapittg From Sip

The structure of Crystal Structure of SIAH1 Sbd Bound to the Peptide Ekpaavvapittg From Sip, PDB code: 2a25 was solved by E.Santelli, M.Leone, C.Li, T.Fukushima, N.E.Preece, A.J.Olson, K.R.Ely, J.C.Reed, M.Pellecchia, R.C.Liddington, S.Matsuzawa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.11 / 2.20
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	47.635, 107.761, 78.414, 90.00, 90.00, 90.00
R / Rfree (%)	21.3 / 25.2

The binding sites of Zinc atom in the Crystal Structure of SIAH1 Sbd Bound to the Peptide Ekpaavvapittg From Sip (pdb code 2a25). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of SIAH1 Sbd Bound to the Peptide Ekpaavvapittg From Sip, PDB code: 2a25:

Zinc binding site 1 out of 1 in the Crystal Structure of SIAH1 Sbd Bound to the Peptide Ekpaavvapittg From Sip


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of SIAH1 Sbd Bound to the Peptide Ekpaavvapittg From Sip within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn601 b:23.7 occ:1.00 NE2 A:HIS147 2.0 16.9 1.0 NE2 A:HIS152 2.1 26.2 1.0 SG A:CYS128 2.3 23.1 1.0 SG A:CYS135 2.3 23.5 1.0 CE1 A:HIS147 2.9 14.1 1.0 CE1 A:HIS152 3.0 27.6 1.0 CD2 A:HIS152 3.1 23.9 1.0 CD2 A:HIS147 3.1 16.7 1.0 CB A:CYS135 3.2 28.6 1.0 CB A:CYS128 3.2 26.1 1.0 ND1 A:HIS147 4.1 17.9 1.0 ND1 A:HIS152 4.2 25.2 1.0 CB A:TRP137 4.2 25.9 1.0 CG A:HIS152 4.2 26.3 1.0 CG A:HIS147 4.2 20.3 1.0 CA A:CYS128 4.5 25.7 1.0 CA A:CYS135 4.6 29.2 1.0 SG A:CYS130 4.8 34.0 1.0 CG A:TRP137 4.9 24.1 1.0

E.Santelli, M.Leone, C.Li, T.Fukushima, N.E.Preece, A.J.Olson, K.R.Ely, J.C.Reed, M.Pellecchia, R.C.Liddington, S.Matsuzawa. Structural Analysis of SIAH1-Siah-Interacting Protein Interactions and Insights Into the Assembly of An E3 Ligase Multiprotein Complex J.Biol.Chem. V. 280 34278 2005.
ISSN: ISSN 0021-9258
PubMed: 16085652
DOI: 10.1074/JBC.M506707200